Chiefs-Chargers Week 11 Odds, Lines and Spread

The Chiefs are large road favorites in Week 11 against the Chargers. The Chiefs won the first matchup in Week 2.

The Chiefs opened as 6.5-point road favorites versus their AFC West rival Chargers for Sunday Night Football.

Kansas City won the first matchup this season at Arrowhead, 27-24.

The Chiefs currently lead the AFC West by two games and could all but wrap up the division at SOFI stadium on Sunday.

Patrick Mahomes and crew have remained the top offense in the NFL, despite losing Tyreek Hill to the Dolphins. The Chiefs are averaging 30 points per game this season, with Mahomes targeting all of his many weapons which includes newcomer Kadarius Toney, in addition to Travis KelceJuJu Smith-SchusterMarquez Valdes-Scantling, and Mecole Hardman.

Even with Smith-Schuster and Hardman possibly missing this contest due to injuries, Mahomes is expected to get the best of a beat-up Chargers’ defense that has allowed plenty of big plays. The Chargers yield 25.3 points per game, and they are very easy to run on. Expect to also see plenty of rookie running back Isaiah Pacheco in this matchup.

The Chiefs are averaging 423 total yards per game this year, while the Chargers are allowing 356.

The Chargers have been struggling offensively this season. Justin Herbert has been playing injured and without top receiver Keenan Allen for much of the season. Mike Williams has the chance to return this week after missing multiple weeks with a high-ankle sprain, and Austin Ekeler continues to be a versatile weapon out of the backfield.

Los Angeles averages 22.2 points per game this year. The Kansas City defense is beatable, allowing an average of 22.9 points per game this year, with much of it coming through the air. Herbert could be in line for a good game.

The Chargers average 350 total yards per game, while the Chiefs are allowing 347.

Chiefs vs. Chargers Odds

Moneyline: KANSAS CITY (-300) | LOS ANGELES (+240)
Spread: KC -6.5 (-110) | LAC +6.5 (-110)
Total: 49.5 – Over (-118) | Under (+100)
Game Info: Nov. 20, 2022 | 8:20 p.m. ET | NBC

Chiefs Straight-Up Record: 7-2
Chiefs Against The Spread Record: 4-5

Chargers Straight-Up Record: 5-4
Chargers Against The Spread Record: 6-3

Bet on Chiefs-Chargers at SI Sportsbook

Odds and Betting Insights

The Chiefs are 4-5 against the spread, while the Chargers are 6-3. The total has gone over in four Chiefs’ games (44.4%) and four Chargers’ games (44.4%).

Kansas City has won three of the last five head-to-head matchups, and the under has hit in three of those five.

Bettors can take part in SI Sportsbook’s free Perfect 10 contest each week during the NFL season. The weekly game requires bettors to make 10 selections against the spread for a chance at a share of a $10,000 prize. Every bettor who picks at least six games correctly will be awarded consolation prizes in the form of free bets.

Get fantasy and betting analysis in your inbox by signing up for the Winners Club newsletter

Check the Latest Odds from SI Sportsbook

More Betting, Fantasy and NFL:
Week 11 NFL Spreads, Matchups
How to Bet on the World Cup
Week 11 Start ’Em, Sit ’Em: RB
NFL Power Rankings


Published
Jennifer Piacenti
JENNIFER PIACENTI

Jennifer Piacenti is a fantasy sports and betting analyst for Sports Illustrated. She serves as a host for Sirius XM Fantasy Sports Radio and has her own podcast, “Waiver Wired,” on the Extra Points podcast network. Piacenti is also a featured expert on MLB Network’s “Bettor’s Eye” and is a member of the esteemed Tout Wars, the fantasy baseball battle of the experts. She is a member of the Fantasy Sports Writers Association and is a 2020 Scott Fish Bowl finalist.