NFL Week 12 Betting Guide: Odds for Every Game on Sunday

There are eleven matchups on Sunday and all but one have a spread of less than 3.5 points.
NFL Week 12 Betting Guide: Odds for Every Game on Sunday
NFL Week 12 Betting Guide: Odds for Every Game on Sunday /

If you haven’t joined in the fun yet, pop on over to SI Sportsbook and put in your free entry today for Week 12. If you pick all 10 of the winners against the spread, you could win up to $10,000.

So, what do you have to lose?

That’s right. Absolutely nothing. Plus, the more picks you make correctly, the more free bets you can earn. Look for our expert picks this Friday as an added bonus.

Perfect 10 w Frankie_11

Here are this week’s lines for SI Sportsbook’s Perfect Ten:

Saints at Falcons

  • Contest Line: Saints +1.5 | Falcons -1.5
  • Game Info: Sunday Nov. 26, 1:00 p.m. ET | FOX

The Saints and Falcons both return from bye for this NFC South divisional matchup. Atlanta is 4-6 ATS this season while New Orleans is 5-5.

Steelers at Bengals

  • Contest Line: Steelers -1.5 | Bengals+1.5
  • Game Info: Sunday Nov. 26, 1:00 p.m. ET | CBS

The Bengals will go to battle without a first-string quarterback, and arguably the Steelers will, too (depending on how you feel about Kenny Pickett). Cincinnati is 5-5 ATS this year, while the Steelers are 6-4.

Jaguars at Texans

  • Contest Line: Jaguars -1.5 |Texans+1.5
  • Game Info: Sunday Nov. 26, 1:00 p.m. ET | CBS

This could be the game of the week, as the surging Texans and with CJ Stroud host the first-place AFC South Falcons and Trevor Lawrence. Look for Jacksonville to run the ball while the Texans air it out vs. a struggling Jacksonville secondary.

Buccaneers at Colts

  • Contest Line: Buccaneers +2.5 | Colts -2.5
  • Game Info: Nov. 26, 1:00 p.m. ET | CBS

Can Gardner Minshew throw for 300+ yards vs. a generous Tampa Bay Bucs secondary? Can Baker Mayfield continue to connect with Mike Evans? This one is likely to be a close one.

Patriots at Giants

  • Contest Line: Patriots -3.5 | Giants +3.5
  • Game Info: Sunday Nov. 26, 1:00 p.m. ET | FOX

Someone get Tommy DeVito some extra chicken cutlets because he’ll be facing a Bill Belichick team that historically isn’t kind to rookies. The Giants pulled off the win last week, but can they cover at home in a game where the total is listed at a mere 33.5?

Panthers at Titans

  • Contest Line: Panthers +3.5| Titans-3.5
  • Game Info: Sunday Nov. 26 , 1:00 p.m. ET | FOX

Two rookie quarterbacks will duel this Sunday in Nashville. The Titans and Derrick Henry will run like mad over a soft Panthers run defense, while Bryce Young will look to connect with Adam Thielen more often. The Panthers are a league-worst 1-9 ATS this season, while the Titans are only 3-7.

Rams at Cardinals

  • Contest Line: Rams +1.5 | Cardinals-1.5
  • Game Info: Sunday Nov. 26, 4:05p.m. ET | FOX

It looks like no one told Kyler Murray to tank, and Matt Stafford could be playing without Cooper Kupp. This one should be a close one. The Rams are 4-6 ATS this year while the Cardinals are 2-9.

Browns at Broncos

  • Contest Line: Browns +2.5 | Broncos -2.5
  • Game Info: Sunday Nov. 26, 4:05 p.m. ET| FOX

Expect the Browns to run on the Broncos this Sunday in what will likely be a low scoring matchup. The Browns are an impressive 7-3 ATS this season despite losing many key pieces, while the surging Broncos have improved to 5-5 ATS.

Chiefs at Raiders

  • Contest Line: Chiefs -9.5 | Raiders +9.5
  • Game Info: Sunday Nov. 26, 4:25 p.m. ET| CBS

The Chiefs are expected to win this one by a large margin, but don’t expect Antonio Pierce’s team to go down without a fight.

Bills at Eagles

  • Contest Line: Bills +3.5| Eagles -3.5
  • Game Info: Sunday Nov. 26, 4:25p.m. ET | CBS

This should be a great game with two of the best mobile passers facing off. The Eagles are favored by more than a field goal at home for the game with the second-highest total of the week at SI Sportsbook.


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Jennifer Piacenti
JENNIFER PIACENTI

Jennifer Piacenti is a fantasy sports and betting analyst for Sports Illustrated. She serves as a host for Sirius XM Fantasy Sports Radio and has her own podcast, “Waiver Wired,” on the Extra Points podcast network. Piacenti is also a featured expert on MLB Network’s “Bettor’s Eye” and is a member of the esteemed Tout Wars, the fantasy baseball battle of the experts. She is a member of the Fantasy Sports Writers Association and is a 2020 Scott Fish Bowl finalist.