Best College Football Picks Straight Up for Every Top 25 Game in Week 14

Reed Wallach | 3 Hours Ago

Texas Longhorns linebacker Anthony Hill Jr. (0) celebrates a stop on fourth down against Kentucky Wildcats in the third quarter during the second half of an NCAA college football game at Darrell K Royal Texas Memorial Stadium, Austin, Texas, Saturday, Nov 24, 2024. / Ricardo B. Brazziell/American-Statesman / USA TODAY NETWORK via Imagn Images

With one week left in the regular season, who will finish the season on a high note? 

There’s plenty to play for for many teams, namely teams like Texas and Texas A&M, who will play for a spot in the SEC Championship Game as well as possibly in the College Football Playoff. Get our picks for each game on who will win straight up below!

Season Record: 149-55

Odds courtesy of FanDuel Sportsbook

Best College Football Picks Straight Up for Week 14

Memphis vs. Tulane Prediction and Pick

Pick: Tulane -530

Oregon State vs. Boise State Prediction and Pick

Pick: Boise State -1250

Oklahoma State vs. Colorado Prediction and Pick

Pick: Colorado -750

The Buffaloes are massive favorites in this game as Oklahoma State is starting its rebuilding process early going to the freshman Maealiuaki Smith. 

The Pokes offense has had flashes all season, but the team has lacked the ability to get any stops on defense and I expect that to be a similar case on Friday against Colorado’s offense. 

Oklahoma State’s defense has allowed the following point totals to opponents last season: 22, 42, 38, 38, 38, 42, 38, 56. It’s not pretty. 

For the Buffaloes, the team’s hopes of making the Big 12 title game is in serious jeopardy, needing some help to breakthrough, but this will be the team’s final home game with a favorable matchup. 

I view this as an opportunity for the Buffs to make a final statement in terms of Travis Hunter’s Heisman Trophy candidacy. I think the team comes out and takes the top off the Cowboys defense with a handful of explosive plays and finds plenty of scoring chances. 

In a game that can quickly devolve into an offensive showcase, I’ll side with the Buffaloes offense as the clear constant in this game.

Mississippi State vs. Ole Miss Prediction and Pick

Pick: Ole Miss -4000

Georgia Tech vs. Georgia Prediction and Pick

Pick: Georgia -1400

Michigan vs. Ohio State Prediction and Pick

Pick: Ohio State -1300

Tennessee vs. Vanderbilt Prediction and Pick

Pick: Vanderbilt +330

South Carolina vs. Clemson Prediction and Pick

Pick: Clemson -134

Two elite defensive lines meet two suspect offensive lines in this in-state matchup with College Football Playoff stakes. 

I’m going to pump the brakes on South Carolina’s offensive onslaught as the team has been much improved, but still has allowed nearly as many sacks as any team in the country, bottom 10 in the nation. 

This will be a step up in class for the Gamecocks on the road, and while I do have some concerns about the Tigers ability to block South Carolina, I do believe the team can win a tight game at home. 

Make sure to keep an eye on Clemson’s injury report ahead of this one after suffering several injuries on the offensive line in recent weeks. 

UTSA vs. Army Prediction and Pick

Pick: Army -285

Illinois vs. Northwestern Prediction and Pick

Pick: Illinois -300

Maryland vs. Penn State Prediction and Pick

Pick: Penn State -4000

Notre Dame vs. USC Prediction and Pick

Pick: Notre Dame -275

Auburn vs. Alabama Prediction and Pick

Pick: Auburn +330

Miami (Florida) vs. Syracuse Prediction and Pick

Pick: Miami (Florida) –325

Cal vs. SMU Prediction and Pick

Pick: SMU -490

Arizona State vs. Arizona Prediction and Pick

Pick: Arizona State -315

Arizona State is one win away from a Big 12 title game appearance in its first season in the league, but the team must get past in-state foe Arizona on the road. 

Last season, the roles were reversed for these two as Arizona was enjoying a big season and Arizona State was in disarray and the Wildcats won 59-23.

 I see ASU getting some revenge against an Arizona team that has been rarely competitive in Big 12 play. Outside of a lone win against a Houston team that is at the outside of a rebuild, the Wildcats have lost six of eight Big 12 games by double digits. 

Arkansas vs. Missouri Prediction and Pick

Pick: Missouri -150

Long-time rivals meet and I favor the home team in this one that has righted the ship with a fully healthy backfield that includes veteran quarterback Brady Cook and transfer running back Nate Noel. 

Arkansas has been a frisky all season long, but typically in the role as a big underdog where staying within ear shot cashes tickets against the spread, not to win on the road. 

The Hogs got to bowl eligibility last week, I like Mizzou to take care of business at home. 

Purdue vs. Indiana Prediction and Pick

Pick: Indiana -5000

Washington vs. Oregon Prediction and Pick

Pick: Oregon -1050

Kansas State vs. Iowa State Prediction and Pick

Pick: Kansas State +118

Texas vs. Texas A&M Prediction and Pick

Pick: Texas -225

While there are plenty of concerns for Texas going on the road to face Texas A&M in a renewed rivalry matchups, I will side with the Longhorns to end the Aggies quest for a College Football Playoff berth. 

The Longhorns faced a Collin Klein-led offense last season and while the scoreboard showed 30 points for Kansas State in an overtime victory, Klein’s offense only had about five yards per play. 

This is a limited Texas A&M offense that is over-reliant on Marcel Reed as a rusher as he is still a limited passer, which makes me comfortable with trusting this Longhorns defense to shut down the home underdog and find enough answers to win a low scoring affair. 

Nevada vs. UNLV Prediction and Pick

Pick: UNLV -1050

Houston vs. BYU Prediction and Pick

Pick: Houston +400

Look out for this one late at night. 

We’ve seen Houston pushed out of a few games due to a negative game script, but I wonder if the team can get its ground game going against BYU, who is below the national average in EPA/Rush and struggles to get pressure on the quarterback. 

If Houston can shorten this game, I believe the team is live to spring the titanic upset on Saturday night with BYU still in the mix for a Big 12 title berth. 

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