NFL Straight-Up Moneyline Picks for Every Game in Week 1

The Sports Illustrated team breaks down their picks to win all 16 games in Week 1 of the 2024 NFL season.

SI Staff | Sep 4, 2024

The Sports Illustrated team has made their picks for every single NFL Week 1 game. /

The wait is finally over. The NFL is back!

Each week, Sports Illustrated's team of NFL insiders and betting insiders will make their picks to win every single game. That's 272 regular season games and 272 predictions.

In this article, we're not taking into account point spreads, totals, or player props. All we're trying to do is pick the winner of each game. We'll track performance based on overall record, last week's record and total betting units won or lost throughout the season.

Introducing this year's team who will be making picks all season long:

Albert Breer, Senior NFL Reporter
Connor Orr, Senior Writer
Mitch Goldich, Senior Editor
Matt Verderame, NFL Staff Writer
Gilberto Manzano, NFL Staff Writer
Jennifer Piacenti, Senior Betting and Fantasy Analyst
Peter Dewey, Senior Editor Betting
Iain MacMillan, Senior Editor Betting

Without further ado, let's take a look at who everyone is picking for all 16 NFL Week 1 games. The moneyline odds listed are via DraftKings Sportsbook.

NFL Week 1 picks /

Ravens (+124) vs. Chiefs (-148) Picks

Albert Breer: Chiefs
Conor Orr: Chiefs
Mitch Goldich: Chiefs
Matt Verderame: Chiefs
Gilberto Manzano: Chiefs
Jennifer Piacenti: Chiefs
Peter Dewey: Chiefs
Iain MacMillan: Ravens

Packers (+120) vs. Eagles (-142) Picks

Albert Breer: Packers
Conor Orr: Packers
Mitch Goldich: Eagles
Matt Verderame: Packers
Gilberto Manzano: Eagles
Jennifer Piacenti: Packers
Peter Dewey: Packers
Iain MacMillan: Eagles

Cardinals (+225) vs. Bills (-278) Picks

Albert Breer: Bills
Conor Orr: Cardinals
Mitch Goldich: Bills
Matt Verderame: Bills
Gilberto Manzano: Bills
Jennifer Piacenti: Bills
Peter Dewey: Bills
Iain MacMillan: Cardinals

Patriots (+330) vs. Bengals (-425) Picks

Albert Breer: Bengals
Conor Orr: Bengals
Mitch Goldich: Bengals
Matt Verderame: Bengals
Gilberto Manzano: Bengals
Jennifer Piacenti: Bengals
Peter Dewey: Bengals
Iain MacMillan: Bengals

Jaguars (+140) vs. Dolphins (-166) Picks

Albert Breer: Dolphins
Conor Orr: Dolphins
Mitch Goldich: Dolphins
Matt Verderame: Dolphins
Gilberto Manzano: Jaguars
Jennifer Piacenti: Dolphins
Peter Dewey: Jaguars
Iain MacMillan: Dolphins

Texans (-142) vs. Colts (+120) Picks

Albert Breer: Texans
Conor Orr: Colts
Mitch Goldich: Texans
Matt Verderame: Texans
Gilberto Manzano: Texans
Jennifer Piacenti: Texans
Peter Dewey: Texans
Iain MacMillan: Colts

Titans (+170) vs. Bears (-205) Picks

Abert Breer: Bears
Conor Orr: Bears
Mitch Goldich: Titans
Matt Verderame: Bears
Gilberto Manzano: Bears
Jennifer Piacenti: Bears
Peter Dewey: Bears
Iain MacMillan: Titans

Steelers (+124) vs. Falcons (-148) Picks

Albert Breer: Falcons
Conor Orr: Steelers
Mitch Goldich: Steelers
Matt Verderame: Falcons
Gilberto Manzano: Falcons
Jennifer Piacenti: Falcons
Peter Dewey: Falcons
Iain MacMillan: Falcons

Vikings (-118) vs. Giants (-102) Picks

Albert Breer: Giants
Conor Orr: Giants
Mitch Goldich: Vikings
Matt Verderame: Giants
Gilberto Manzano: Giants
Jennifer Piacenti: Vikings
Peter Dewey: Giants
Iain MacMillan: Vikings

Panthers (+164) vs. Saints (-198) Picks

Albert Breer: Saints
Conor Orr: Panthers
Mitch Goldich: Saints
Matt Verderame: Saints
Gilberto Manzano: Saints
Jennifer Piacenti: Saints
Peter Dewey: Saints
Iain MacMillan: Saints

Broncos (+195) vs. Seahawks (-238) Picks

Albert Breer: Broncos
Conor Orr: Seahawks
Mitch Goldich: Seahawks
Matt Verderame: Seahawks
Gilberto Manzano: Seahawks
Jennifer Piacenti: Seahawks
Peter Dewey: Broncos
Iain MacMillan: Broncos

Raiders (+136) vs. Chargers (-162) Picks

Albert Breer: Chargers
Conor Orr: Chargers
Mitch Goldich: Chargers
Matt Verderame: Chargers
Gilberto Manzano: Raiders
Jennifer Piacenti: Chargers
Peter Dewey: Chargers
Iain MacMillan: Chargers

Cowboys (+114) vs. Browns (-135) Picks

Albert Breer: Browns
Conor Orr: Browns
Mitch Goldich: Browns
Matt Verderame: Cowboys
Gilberto Manzano: Browns
Jennifer Piacenti: Cowboys
Peter Dewey: Cowboys
Iain MacMillan: Browns

Commanders (+154) vs. Buccaneers (-185)

Albert Breer: Buccaneers
Conor Orr: Buccaneers
Mitch Goldich: Buccaneers
Matt Verderame: Buccaneers
Gilberto Manzano: Commanders
Jennifer Piacenti: Commanders
Peter Dewey: Buccaneers
Iain MacMillan: Buccaneers

Rams (+142) vs. Lions (-170)

Albert Breer: Lions
Conor Orr: Rams
Mitch Goldich: Lions
Matt Verderame: Lions
Gilberto Manzano: Lions
Jennifer Piacenti: Lions
Peter Dewey: Lions
Iain MacMillan: Rams

Jets (+164) vs. 49ers (-198)

Albert Breer: 49ers
Conor Orr: 49ers
Mitch Goldich: 49ers
Matt Verderame: 49ers
Gilberto Manzano: 49ers
Jennifer Piacenti: 49ers
Peter Dewey: 49ers
Iain MacMillan: 49ers