NFL Straight-Up Moneyline Picks for Every Game in Week 2

The Sports Illustrated team breaks down their picks to win all 16 games in Week 2 of the 2024 NFL season.

SI Staff | Sep 11, 2024

The Sports Illustrated team breaks down their picks to win all 16 games in Week 2 of the 2024 NFL season. /

The 2024 NFL season has officially begun and we're one week into the action.

Week 1 was a great week for favorites, with them going 13-3 overall. The Steelers, Patriots, and Bengals were the only underdogs able to pull off the upset. Let's take a look at how the Sports Illustrated team did with their Week 1 picks:

Albert Breer, Senior NFL Reporter (10-6, -0.04 units)
Mitch Goldich, Senior Editor (13-3 +5.31 units)
Gilberto Manzano, NFL Staff Writer (10-6, -2.05 units)
Connor Orr, Senior Writer (8-8, -2.91 units)
John Pluym, NFL Managing Editor (10-6, -0.48 units)
Matt Verderame, NFL Staff Writer (12-4, +3.15 units)
Jennifer Piacenti, Senior Betting and Fantasy Analyst (12-4, +3.45 units)
Peter Dewey, Senior Editor Betting (10-6, +0.12 units)
Iain MacMillan, Senior Editor Betting (8-8, -3.26 units)

Mitch Goldich crushed Week 1, sporting an eye-popping 13-3 record for +5.31 units, including correctly calling the Pittsburgh Steelers to upset the Atlanta Falcons as 3-point underdogs.

Jennifer Piacenti (12-4, +3.45 units) and Matt Verderame (12-4, +3.15 units) rounds out the top three performers for Week 1. Iain MacMillan finished at the bottom of the Week 1 standings at 8-8 for -3.26 units, getting too aggressive backing underdogs in a week that was dominated by favorites.

With Week 1 now in the rearview mirror, let's take a look at which side the Sports Illustrated team is backing for all 16 Week 2 games.

All odds listed are via DraftKings Sportsbook.

NFL Week 2 picks /

Bills (+114) vs. Dolphins (-135)

Albert Breer: Bills
Mitch Goldich: Bills
Gilberto Manzano: Bills
Connor Orr: Bills
John Pluym: Bills
Matt Verderame: Bills
Jennifer Piacenti: Bills
Peter Dewey: Bills
Iain MacMillan: Dolphins

Raiders (+350) vs. Ravens (-455)

Albert Breer: Ravens
Mitch Goldich: Ravens
Gilberto Manzano: Ravens
Connor Orr: Ravens
John Pluym: Ravens
Matt Verderame: Ravens
Jennifer Piacenti: Ravens
Peter Dewey: Ravens
Iain MacMillan: Ravens

Saints (+250) vs. Cowboys (-310)

Albert Breer: Cowboys
Mitch Goldich: Cowboys
Gilberto Manzano: Cowboys
Connor Orr: Saints
John Pluym: Cowboys
Matt Verderame: Cowboys
Jennifer Piacenti: Cowboys
Peter Dewey: Cowboys
Iain MacMillan: Saints

Seahawks (-170) vs. Patriots (+142)

Albert Breer: Seahawks
Mitch Goldich: Seahawks
Gilberto Manzano: Seahawks
Connor Orr: Patriots
John Pluym: Patriots
Matt Verderame: Seahawks
Jennifer Piacenti: Seahawks
Peter Dewey: Seahawks
Iain MacMillan: Seahawks

Colts (-162) vs. Packers (+136)

Albert Breer: Colts
Mitch Goldich: Colts
Gilberto Manzano: Colts
Connor Orr: Colts
John Pluym: Colts
Matt Verderame: Colts
Jennifer Piacenti: Colts
Peter Dewey: Colts
Iain MacMillan: Colts

49ers (-258) vs. Vikings (+210)

Albert Breer: 49ers
Mitch Goldich: 49ers
Gilberto Manzano: 49ers
Connor Orr: 49ers
John Pluym: 49ers
Matt Verderame: 49ers
Jennifer Piacenti: 49ers
Peter Dewey: 49ers
Iain MacMillan: 49ers

Chargers (-278) vs. Panthers (+225)

Albert Breer: Chargers
Mitch Goldich: Chargers
Gilberto Manzano: Chargers
Connor Orr: Chargers
John Pluym: Chargers
Matt Verderame: Chargers
Jennifer Piacenti: Chargers
Peter Dewey: Chargers
Iain MacMillan: Chargers

Jets (-180) vs. Titans (+150)

Albert Breer: Jets
Mitch Goldich: Jets
Gilberto Manzano: Titans
Connor Orr: Jets
John Pluym: Jets
Matt Verderame: Jets
Jennifer Piacenti: Jets
Peter Dewey: Jets
Iain MacMillan: Jets

Giants (+102) vs. Commanders (-122)

Albert Breer: Commanders
Mitch Goldich: Commanders
Gilberto Manzano: Commanders
Connor Orr: Giants
John Pluym: Commanders
Matt Verderame: Commanders
Jennifer Piacenti: Commanders
Peter Dewey: Giants
Iain MacMillan: Commanders

Browns (+136) vs. Jaguars (-162)

Albert Breer: Browns
Mitch Goldich: Jaguars
Gilberto Manzano: Jaguars
Connor Orr: Browns
John Pluym: Jaguars
Matt Verderame: Jaguars
Jennifer Piacenti: Jaguars
Peter Dewey: Jaguars
Iain MacMillan: Jaguars

Buccaneers (+270) vs. Lions (-340)

Albert Breer: Lions
Mitch Goldich: Lions
Gilberto Manzano: Lions
Connor Orr: Buccaneers
John Pluym: Lions
Matt Verderame: Lions
Jennifer Piacenti: Lions
Peter Dewey: Buccaneers
Iain MacMillan: Lions

Rams (+102) vs. Cardinals (-122)

Albert Breer: Rams
Mitch Goldich: Rams
Gilberto Manzano: Cardinals
Connor Orr: Rams
John Pluym: Cardinals
Matt Verderame: Rams
Jennifer Piacenti: Rams
Peter Dewey: Cardinals
Iain MacMillan: Cardinals

Bengals (+205) vs. Chiefs (-250)

Albert Breer: Chiefs
Mitch Goldich: Chiefs
Gilberto Manzano: Chiefs
Connor Orr: Chiefs
John Pluym: Chiefs
Matt Verderame: Chiefs
Jennifer Piacenti: Chiefs
Peter Dewey: Chiefs
Iain MacMillan: Chiefs

Steelers (-155) vs. Broncos (+130)

Albert Breer: Broncos
Mitch Goldich: Steelers
Gilberto Manzano: Steelers
Connor Orr: Steelers
John Pluym: Steelers
Matt Verderame: Steelers
Jennifer Piacenti: Steelers
Peter Dewey: Steelers
Iain MacMillan: Broncos

Bears (+235) vs. Texans (-290)

Albert Breer: Texans
Mitch Goldich: Texans
Gilberto Manzano: Texans
Connor Orr: Texans
John Pluym: Texans
Matt Verderame: Texans
Jennifer Piacenti: Texans
Peter Dewey: Texans
Iain MacMillan: Texans

Falcons (+240) vs. Eagles (-298)

Albert Breer: Eagles
Mitch Goldich: Eagles
Gilberto Manzano: Eagles
Connor Orr: Eagles
John Pluym: Eagles
Matt Verderame: Eagles
Jennifer Piacenti: Eagles
Peter Dewey: Eagles
Iain MacMillan: Eagles