College football Week 4 odds: Betting odds for most notable matchups

Early betting odds for the most notable Week 4 college football games.

Two Pac-12 conference matchups featuring Top 25 teams highlight the Week 4 college football betting slate, as the ninth-ranked UCLA Bruins visit the 16th-ranked Arizona Wildcats and the 13th-ranked Oregon Ducks host the 18th-ranked Utah Utes.

The Bruins are consensus 3.5-point road favorites at sportsbooks monitored by OddsShark.com, while the Ducks are still waiting to see who will start at quarterback for them heading into the Utah game.

UCLA is coming off a 24–23 home win against the BYU Cougars last Saturday but failed to cover the number for the first time this season as a 16.5-point favorite. Meanwhile, Arizona is also 2–1 against the spread, covering two in a row following a 77–13 rout of the Northern Arizona Lumberjacks as 34.5-point home chalk last week.

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Utah begins league play after topping the Fresno State Bulldogs 45–24 and covering as a 12-point road favorite but has struggled against Oregon recently. The Utes have gone 1–2 ATS in losing the last three meetings with the Ducks by an average of 18 points according to the OddsShark College Football Database.

BYU will play its second road matchup against a Big Ten school in four games so far this year when the team visits the Michigan Wolverines as a 5.5-point underdog.

The Cougars are a perfect 3–0 ATS after upsetting the Nebraska Cornhuskers 33–28 as 4.5-point road dogs in their season opener back on Sept. 5 and following that up with a 35–24 win over the Boise State Broncos as two-point home dogs behind freshman quarterback Tanner Mangum.

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The top two teams in the country from the Big Ten will also host a pair of Mid-American Conference schools as big favorites when the top-ranked Ohio State Buckeyes meet the Western Michigan Broncos and the second-ranked Michigan State Spartans face the Central Michigan Chippewas on Saturday.

The Buckeyes are 23–0 straight-up against MAC foes but fell to 6–3 ATS in their past nine games following a 20–13 win over the Northern Illinois Huskies last week. They are 31-point chalk while the Spartans are -26.5 against the Chippewas and have yet to cover this year.