Spread & Over/Under Predictions For Georgia Tech vs No. 21 Louisville

After a tough loss on the road to Notre Dame, Georgia Tech is back at home tomorrow to face one of the best teams in the ACC, Louisville. Pat Kelsey has the Cardinals near the top of the conference in just his first season on the job and they should be one of the ACC teams that makes the NCAA Tournament.
Louisville (16-5, 9-1 ACC) comes to Atlanta riding a 10-game winning streak, the last eight of which were conference games, and is one game behind Duke in second place in the ACC standings. The Cardinals, 5-0 on the road in ACC games this season, won seven of those eight by double digits.
Louisville is the fifth top-25 team Tech has faced this season and the first since Duke back on Dec. 21. The Yellow Jackets are 0-4 against top-25 teams this season after going 3-1 against them in 2023-24.
A win Saturday would also be Tech’s first against a Quad 1 opponent in the NCAA’s NET rankings this season (Louisville is No. 25). The Yellow Jackets are 0-5 against Quad 1 opponents this season after going 4-7 against such teams last year. Two more Quad 1 opportunities exist on Tech’s schedule, Clemson (30) and Wake Forest (69), both on the road.
Tech is 2-5 against Louisville at home since the Cardinals joined the ACC, including an 83-67 win two seasons ago (Feb. 25, 2023).
Tech is 7-11 against Louisville all-time when the Cardinals have been ranked. Most recently, Tech defeated No. 5 U of L, 64-58, on Feb. 12, 2020.
Unlike last season, when 14 of Georgia Tech’s 20 ACC games were decided by less than 10 points, only four of the Yellow Jackets’ first 10 conference games this season have been decided by single digits, and two of those have occurred in Tech’s last two games (71-64 win over Virginia Tech, 71-68 loss at Notre Dame).
Five Yellow Jackets have averages in double-digits for ACC games – Lance Terry (15.1), Javian McCollum (14.1), Duncan Powell (13.3), Naithan George (11.5) and Baye Ndongo (11.0).
Of the four teams added in the 2013 expansion of the ACC, Tech had the longest history with Louisville, meeting 28 times prior to the Cardinals joining the conference.
Louisville has won 14 of the last 16 games in the series and is 12-2 against Tech since becoming a member of the ACC. Tech’s only wins were a 64-58 triumph over a Cardinals’ team ranked No. 5 in the nation at home on Feb. 12, 2020, and an 83-67 home win on Feb. 25, 2023.
After a 12-year hiatus, Tech was 2-2 vs. Louisville when both teams were members of the Metro Conference in the late 1970s. Dwane Morrison was the Yellow Jackets’ head coach for all those games, and Denny Crum was on the Cardinals’ bench.
After another long break, the teams met 13 times between 1988 and 1999, with Bobby Cremins and Crum on the opposing benches in all those games. The Yellow Jackets went 8-5 against the Cardinals during this time. Three of the meetings took place at Alexander Memorial Coliseum, and six at Freedom Hall.
Odds
According to Fanduel Sportsbook, the Cardinals are 8.5 point favorites and the total is at 149.5.
Prediction
Louisville and Georgia Tech have both been dealing with injuries this season, but the Cardinals have done so far better. Pat Kelsey has this team playing really well right now and with the Yellow Jackets down a number of key players and playing with zero consistency, it is tough for me to pick the Yellow Jackets.
Final Score Louisville 77, Georgia Tech 66 (Louisville -8.5 and Under)
Related Links
How to Watch the 2025 Reeses Senior Bowl: Kickoff Time, TV Channel, Roster
Georgia Tech Played in Five of the Best College Football Games of 2024, per ESPN