Opening Line: Indiana an Underdog For First Time in 2024 Against Ohio State

Here's the point spread and over/under for Indiana's road game against Ohio State, plus betting results from throughout the season.

Indiana's Terry Jones Jr. (12) celebrates against Michigan at Memorial Stadium. / Rich Janzaruk/Herald-Times / USA TODAY NETWORK via Imagn Images

BLOOMINGTON, Ind. – Indiana will be in uncharted territory when it plays at Ohio State. For the first time all season, Indiana is an underdog.

Ohio State opened as 9.5-point favorites over the Hoosiers, but the line has moved to 12 points in the Buckeyes' favor, according to Action Network on Monday morning. The over/under is 52.5 points. Indiana is a plus-335 underdog on the moneyline, and Ohio State's moneyline odds are minus-440.

The game is schedule for Nov. 23 at noon ET at Ohio Stadium in Columbus, Ohio. It will be broadcast on FOX.

Indiana has a bye week before what could be a top-five matchup, depending on what happens around the country. Ohio State plays at Northwestern on Saturday before hosting the Hoosiers. In Sunday's AP Top 25 Poll, Ohio State was ranked No. 2 and Indiana came in at No. 5.

Indiana football against the spread in 2024

• Week 1: Indiana did not cover a 25.5-point spread as favorites in its 31-7 win at home against Florida International. The game went under 52 points.

• Week 2: Indiana covered a 44.5-point spread as favorites in its 77-3 win at home against Western Illinois. The game went over 54.5 points.

• Week 3: Indiana covered a 4-point spread as favorites in its 42-13 win at UCLA. The game went over 46.5 points.

• Week 4: Indiana covered a 28.5-point spread as a favorite in its 52-14 win at home against Charlotte. The game went over 51 points.

• Week 5: Indiana covered a 7.5-point spread as a favorite in its 42-28 win at home against Maryland. The game went over 50.5 points.

• Week 6: Indiana covered a 13-point spread as a favorite in its 41-24 win at Northwestern. The game went over 40 points.

• Week 7: Bye

• Week 8: Indiana covered a 6.5-point spread as a favorite in its 56-7 win at home against Nebraska. The game went over 49 points.

• Week 9: Indiana covered a 5.5-point spread as a favorite in its 31-17 win at home against Washington. The game went under 54 points.

• Week 10: Indiana covered a 7.5-point spread as a favorite in its 47-10 win at Michigan State. The game went over 53.5 points.

• Week 11: Indiana did not cover a 14.5-point spread as a favorite in its 20-15 win at home against Michigan. The game went under 47.5 points.

• Week 12: Bye

Ohio State leads the all-time series against Indiana 79-12-5. The Buckeyes have a 28-game win streak against the Hoosiers, dating back to 1991. The teams tied 27-27 during the 1990 season, and Indiana's last win over Ohio State came in 1988, when the Hoosiers won 41-7 in Bloomington.

Indiana also defeated Ohio State 31-10 during the 1987 season, snapping a winless streak against the Buckeyes since 1951. Five of Indiana's win in this series came between 1901-13.

In coach Curt Cignetti's first season, Indiana secured the first 10-win season in program history Saturday with a 20-15 win over Michigan. That was the first time since Week 1 against Florida International that Indiana did not cover the point spread.

The Hoosiers led the Wolverines 17-3 at halftime, but generated just 18 yards of total offense in the second half. However, the defense made stops in critical situations to keep their undefeated season alive.

Ohio State is currently 8-1 overall and 5-1 in Big Ten play. The Buckeyes' lone loss this year came on Oct. 12 at No. 1 Oregon, where they fell 32-31. That gave Ohio State its first and only loss in Big Ten play, a stretch that includes wins over Michigan State, Iowa, Nebraska, Penn State and Purdue.

Most recently, the Buckeyes won 45-0 at home against Purdue. They also beat Akron, Western Michigan and Marshall in nonconference play.

Related stories on Indiana football

• AP TOP 25 POLL: Indiana moves up three spots in the poll as the Hoosiers creep close to their best-ever ranking. CLICK HERE

• INDIANA ESCAPES WITH 20-15 WIN: Indiana holds off Michigan to earn a 20-15 win to improve to 10-0. CLICK HERE.

• THE DAY AFTER: How did Hoosiers On SI do in its pregame three keys and score prediction for the Michigan game? CLICK HERE

• FEAR NOT, THE DEFENSE HAS THIS: Todd Golden writes about how it got a bit scary at Memorial Stadium on Saturday ... until the Indiana defense got on the field. CLICK HERE.

• WHAT CIGNETTI SAID: Here's everything Cignetti said to the media after the Michigan win. CLICK HERE

• ROLES REVERSED FOR MICHIGAN: Indiana rarely loses to Michigan, but the roles are reversed as Indiana improved to 10-0 at the expense of the Wolverines. CLICK HERE.

• LIVE BLOG: Follow along as Hoosiers On SI writes about the events of the game as they happened. Re-live Indiana's thrilling 20-15 victory over Michigan. CLICK HERE.

• DREW EVANS OUT FOR SEASON: Indiana has lost guard Drew Evans for the season according to the availability report for the Indiana-Michigan game on Saturday. CLICK HERE.