Louisville Opens as Road Favorite at Virginia

The Cardinals head back on the road to face the Cavaliers in their first ACC matchup away from home.
Louisville's Isaac Guerendo ran for a touchdown against Virginia in L&N Stadium.
Louisville's Isaac Guerendo ran for a touchdown against Virginia in L&N Stadium. / Scott Utterback/Courier Journal / USA TODAY NETWORK
In this story:

LOUISVILLE, Ky. - While the Louisville football program is coming off of a disjointed home loss, oddsmakers are liking them to snap their two-game skid when they travel to Virginia.

According to DraftKings, the Cardinals have opened up as a 7.0-point favorite over the home Cavaliers. The over/under has not yet been set.

Once again, mistakes and miscues spelled doom for Louisville (3-2, 1-1 ACC), eventually handing them a 34-27 loss to SMU. The Cardinals gave up 481 total yards of offense to the Mustangs, while penalties, lackluster execution and questionable play calling handicapped their own offense.

As for Virginia (4-1, 2-0 ACC), they look like they have finally turned things around under head coach Tony Elliott. They've already won their most games under the third year head coach, and are coming off of an impressive come-from-behind 24-14 win over Boston College.

Both Louisville and Virginia are 3-2 against-the-spread so far this season. The Cardinals are 0-1 on the road ATS and straight up, while the Cavaliers are 2-1 at home ATS and straight up.

Louisville was able to cover vs. Austin Peay (-38.5), Jax State (-27.5) and Georgia Tech (-8.5); but not at Notre Dame (+6.5) and vs. SMU (-6.5). Virginia covered vs. Richmond (-19.0), at Coastal Carolina (-3.5) and vs. Boston College (-1.5); but were unable to do so at Wake Forest (-1.5) and vs. Maryland (-3.0).

Kickoff vs. Virginia is scheduled for Saturday, Oct. 12 at 3:30 p.m. EST.

(Photo of Isaac Guerendo: Scott Utterback - Courier Journal / USA TODAY NETWORK)

You can follow Louisville Cardinals On SI for future coverage by liking us on Facebook, Twitter/X and Instagram:

Facebook - @LouisvilleOnSI
Twitter/X - @LouisvilleOnSI
Instagram - @louisvilleonsi

You can also follow Deputy Editor Matthew McGavic at @Matt_McGavic on Twitter/X


Published
Matthew McGavic
MATTHEW MCGAVIC

McGavic is a 2016 Sport Administration graduate of the University of Louisville, and a native of the Derby City. He has been covering the Cardinals in various capacities since 2017, with a brief stop in Atlanta, Ga. on the Georgia Tech beat. He is also a co-host of the 'From The Pink Seats' podcast on the State of Louisville network. Video gamer, bourbon drinker and dog lover. Find him on Twitter at @Matt_McGavic