Preview, Predictions & Betting Odds: Angel Reese and LSU take on Caitlin Clark and Iowa in Elite Eight

The rematch is just hours away with the defending National Champions looking to remain hot in the NCAA Tournament.

Tigers Head Coach Kim Mulkey and Hailey Van Lith 11 The LSU Tigers take down the Middle Tennessee / SCOTT CLAUSE/USA TODAY Network / USA

Kim Mulkey and No. 3 seed LSU look to keep the momentum rolling as they hit the court in Albany on Monday night with a chance to punch their ticket to the Final Four once again.

The defending National Champions are red hot with Iowa and Caitlin Clark standing in the way of another step in their title defense journey.

Can Angel Reese and the Tigers take down Clark and the Hawkeyes?

Here's a preview of the showdown in New York, betting odds and a prediction with both programs looking to punch their ticket to the Final Four:

Preview: The Scouting Report

- Two of the main faces of women’s college basketball will meet once again. Angel Reese has recorded nine straight double-doubles for LSU in the NCAA Tournament, tied for a tournament record. Her profile ballooned after she and LSU scored a NCAA Championship game record 102 points to take down Iowa. Iowa’s Caitlin Clark, a generational player, owns the NCAA scoring record and is the first player in Division-I history with 3,800+ points, 1,000+ assists and 950+ rebounds. Both teams have drawn record crowds at home and on the road while also driving historic television ratings. Last year’s championship game drew a women’s basketball record 9.9-million viewers on ABC. Monday’s crowd at MVP Arena will be packed to the brim and the ESPN broadcast is expected to draw well once again as both teams compete for a chance to advance to the Final Four in Cleveland.

- This year’s LSU team is different than the one the beat Iowa last year on April 2. Flau’Jae Johnson, Last-Tear Poa and Reese are the only players on this year’s team that played in the championship game. Hailey Van Lith has experience at this level of the NCAA Tournament, reaching three Elite Eights and one Final Four at Louisville. Aneesah Morrow, a transfer from DePaul, is playing in her first NCAA Tournament as are freshmen Mikaylah Williams and Aalyah Del Rosario.

- Johnson was electric for the Tigers in the Saturday win over UCLA. She had 24 points and 12 rebounds with 2 blocks to help send LSU to the Elite Eight with her second double-double of the year. In postseason play this season, including the SEC Tournament, Johnson is averaging a team-leading 19.7 points, 5.3 rebound with 14 assists, 13 steals and 8 blocks.

- Clark, who is looking to garner National Player of the Year honors for the second straight year, will go down as one of the game’s greatest players. This season she is averaging 31.7 points, 8.9 assists and 7.3 rebounds per game. Everything for Iowa runs through Clark, but she is not the only capable player on the Hawkeye’s roster. Hannah Stuelke averages 14.0 points and 6.8 rebounds for them in the post. Kate Martin scores 12.8 points per game. Because Clark draws so much defensive attention, her teammates capitalize on hitting open shots and making good cuts to the basket because Clark can find them.

Betting Odds: LSU vs. Iowa (Per DraftKings)

The Spread: Iowa is a two-point favorite in this one. (-110)

The MoneyLine: LSU (+110) / Iowa (-130)

The Over/Under: The over/under is set at 168 points. (-110)

Prediction: LSU 81, Iowa 73

LSU's defense remains red hot during the NCAA Tournament, and with a matchup against the nation's top scorer in Caitlin Clark, it'll be a true test for this program. Insert Flau'jae Johnson. The sophomore sensation has been pivotal for the Tigers during their title defense journey. Now, she'll be up against her biggest challenge yet.

It's a winnable game for Mulkey and Co. despite coming into this one as underdogs. Keep Johnson and Reese out of foul trouble and the Tigers have an opportunity to punch their ticket to the Final Four in back-to-back seasons.

The Tigers and Hawkeyes will tipoff at 6:15pm CT on ESPN in one of the most anticipated matchups in all of college basketball this season.