Colorado vs. Oregon odds, spread, line, Week 4 college football game betting picks

The early lines are out for Colorado vs. Oregon on the Week 4 college football schedule

A huge Pac-12 conference tilt is set for an action-packed Week 4 slate this coming weekend in a battle of ranked league foes with Colorado headed out on the road against Oregon in college football's action on Saturday.

Colorado remains perfect through three games, most recently a come-from-behind victory against in-state rival Colorado State, as the Buffaloes rebounded from being down two possessions to take down the Rams in double overtime.

Oregon is posting 587 yards per game as Heisman contender quarterback Bo Nix has 893 yards passing with eight touchdowns so far, aided by a backfield combination good for 229 rushing yards on average each time out.

Here's the latest intel on the game this weekend with early betting lines and trends.

Colorado vs. Oregon game odds

Courtesy of BetMGM

Line: Oregon -19.5
Total: 70.5 (O -110, U -110)
ML: Oregon -1200 | CU +750
FPI pick: Oregon 93.9% to win

Betting trends

+ Colorado is 4-11 against the spread in last 15 games

+ CU is 2-8 ATS in last 10 against Oregon

+ Total went over in Colorado's last 7 games on the road

+ Oregon is 9-3 against the spread in last 12 overall games

+ Total went under in 4 of Oregon's last 6 against Colorado

+ Total went over in 5 of Oregon's last 7 games in Week 4

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Oregon vs. Colorado schedule

When: Sat., Sept. 23
Time: 1:30 p.m. MT, 12:30 p.m. PT
TV: ABC network
Stream live: fuboTV (Try for free)

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