Ohio State vs. Penn State game odds, prediction, how to bet Week 8 college football

Betting intel and predictions for Ohio State vs. Penn State in this huge Big Ten clash

A major Big Ten battle that could help decide what the conference championship game looks like is set for this coming week as a pair of undefeated East Division rivals meet with No. 3 Ohio State hosting No. 7 Penn State on Saturday.

Penn State is coming off one of its most dominant performances, thrashing non-conference foe UMass in a 63-0 rout and playing a balanced offense good for over 426 yards per game, and behind a stifling run-stop allowing under 73 on average.

Ohio State is dealing with prominent injuries at the running back position, meaning it may have to rely more on quarterback Kyle McCord and a passing game still a work in progress, but thanks to dynamic receiver play averages over 300 air yards per game.

Ohio State vs. Penn State game odds

Courtesy of FanDuel

Line: Ohio State -5.5
Total: 48.5 (O-110, U -110)
Moneyline: OSU -205 | PSU +168

Expert prediction

Most analytic models project Ohio State will defeat Penn State.

That includes College Football Power Index, a computer prediction tool that uses data points from both teams to simulate games 20,000 times and pick winners.

The index projects Ohio State will win with 63.4 percent likelihood, as it came out ahead in 12,680 of the computer's 20,000 simulations.

Penn State wins out in the remaining 36.6 percent of projections, or 7,320 sims.

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Penn State at Ohio State schedule

When: Sat., Oct. 21
Time: 12 p.m. Eastern
TV: Fox network
Stream live: fuboTV (Try for free)

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