Ohio State vs. Michigan picks, predictions: Week 13 college football odds, lines

Expert predictions for The Game as Ohio State visits Michigan in this college football classic

It's all on the line this weekend in the 2023 college football regular season finale as two of the sport's most bitter rivals meet in the Big House with conference title and national championship implications involved when Ohio State visits Michigan on Saturday.

• Both are 11-0 overall and 8-0 in conference play, and the winner earns a date in the Big Ten Championship Game against West Division champ Iowa
• Jim Harbaugh won't be on the sideline as he serves the final game of his suspension handed down from the Big Ten for sign-stealing allegations
• Michigan has won the last two in this series, using the game as a launching point to win two Big Ten titles and make the playoff twice
• Michigan is No. 1 nationally in scoring defense, and Ohio State is No. 2

What do the experts think of the matchup? Let's see how the College Football Power Index computer prediction model projects the game.

Ohio State vs. Michigan picks, predictions

College Football Power Index is a computer prediction model devised by analysts that uses data points from both teams to simulate games 20,000 times and pick winners.

Michigan odds: The computers project the Wolverines will win the game in 54.9 percent of their simulations, or 10,980 of the total projections.

Ohio State odds: That leaves the Buckeyes emerging as the winner of the game in the remaining 45.1 percent of sims, or 9,020 predictions.

Point spread: Michigan is a 3.5 point favorite against Ohio State, according to the lines at SI Sportsbook, which set the total at 47.5 points for the game. The line opened at 5.5 points in Michigan's favor, but has moved the other way since the open.

Moneyline: UM -175 | OSU +150

Score prediction? Expect a close one, as the computer simulations forecast Michigan to be favored by just 0.3 points in the game. If so, your bet should be Ohio State +3.5 and Michigan -175.

Bet on Ohio State vs. Michigan here

Join FanDuel here to claim $200 worth of bonus bets after wagering just $5 on any game.

Claim $200 in Bonus Bets instantly when you Bet $5 with DraftKings.

Get $200 in Bonus Bets with Bet365 here when you Bet Just $1 on any college football game.

Get up to $1,000 in Bonus Bets with Points Bet right here.

Or get $1,500 paid back in bonus bets from BetMGM if you don’t win.

---

More college football from SI: Top 25 Rankings | Schedule | Teams

Follow College Football HQ: Bookmark | Rankings | Picks