Oklahoma vs. SMU picks, predictions: College football Week 2 computer picks, game odds, betting lines

Picks and predictions for Oklahoma vs. SMU as the Week 2 college football schedule kicks off with this Big 12 vs. AAC game

Fresh off a historic opening day victory last weekend, Oklahoma stays home in a matchup against SMU in Saturday's college football Week 2 action.

That history the Sooners made came on the heels of a 73-0 victory over Arkansas State, the single highest margin of victory for an opener since the 1917 season. OU ran for 220 yards while almost doubling that production in the air, including our first glimpse at QB recruit Jackson Arnold on the field, while the defense held the Red Wolves to 48 yards rushing.

SMU took down Louisiana Tech in a 24-point victory in its 2023 debut as quarterback Preston Stone threw three touchdown passes and wasn't intercepted while LJ Johnson, Jr. ran for another score on 128 yards rushing on an offense that went over 300 yards before halftime. SMU held Tech to 7 points before a garbage time score with 26 seconds left in regulation. 

Now, the Mustangs embark on a major road game against a Power Five opponent as they look ahead to joining that exclusive club themselves when the school becomes a member of the ACC next season.

What do the experts think of this matchup? Let's see how the College Football Power Index computer prediction model projects the game.

Oklahoma vs. SMU picks, predictions

Oklahoma vs. SMU picks, predictions / USA Today Images

Oklahoma odds: The computers predictably side with the Sooners, who have the 89.9 percent chance to win the game outright, according to the computer models that pick winners by simulating games 20,000 times.

SMU odds: That leaves the Mustangs with the outside 10.1 percent chance to go into Norman and pull off the upset, according to the index.

Point spread: Oklahoma comes into the game as 16.5 point favorites against SMU, according to the lines at SI Sportsbook. Track it live

Total: 70.5 points

Moneyline: OU -800 | SMU +450

Oklahoma predictions: OU places first in the Big 12 and No. 4 nationally on the 133 college football rankings, a jump of 7 places in that poll, projected to be 23.0 points better than an average opponent, and estimated to win 10.9 games this year. FPI says the Sooners are the favorites to win the league title at 49.7 percent.

SMU predictions: Likewise, the Mustangs project as their respective conference's top team, ranking No. 45 nationally on the index, which projects the team will win 9.2 games this year and be 5.4 points better than an average opponent.

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Oklahoma vs. SMU schedule

When: Sat., Sept. 9
Time: 5 p.m. Central
Watch on: ESPN+

College Football Power Index

Football Power Index (FPI) college football rankings and computer prediction model are a measure of team strength that predicts a team’s future performance.

Rankings and scores predictions are based on 20,000 simulations of a team’s season, using a combination of analytics, including scores to date, quality of opponents, and a team’s schedule.

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College football rankings

According to AP top 25 poll

1. Georgia (58)
2. Michigan (2)
3. Alabama
4. Florida State (3)
5. Ohio State
6. USC
7. Penn State
8. Washington
9. Tennessee
10. Notre Dame
11. Texas
12. Utah
13. Oregon
14. LSU
15. Kansas State
16. Oregon State
17. North Carolina
18. Oklahoma
19. Wisconsin
20. Ole Miss
21. Duke
22. Colorado
23. Texas A&M
24. Tulane
25. Clemson

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