USC vs. UCLA picks, predictions: Week 12 college football odds, lines

Expert game predictions for USC vs. UCLA in this college football classic
USC vs. UCLA picks, predictions: Week 12 college football odds, lines
USC vs. UCLA picks, predictions: Week 12 college football odds, lines /

One of college football's premier rivalry games is set for this weekend between two schools that can't be pleased with how their seasons turned out, as USC and UCLA renew hostilities, both out of the College Football Playoff rankings and each facing somewhat uncertain futures in the coaching ranks.

  • Reports have emerged that UCLA is preparing to fire head coach Chip Kelly, although a decision is yet to be made official
  • Bruins fell to 3-4 in Pac-12 play and have lost three of the last five, scoring 17 combined points in the last two weeks
  • USC has relieved defensive coordinator Alex Grinch after a second straight year of vastly under-performing play on that side of the ball
  • The unit helped sink the one-time CFP hopeful Trojans to a 7-4 record overall and a 5-3 mark in conference games
  • Southern Cal has dropped four of the last five, with the win being by 1 point against Cal

What do the experts make of the matchup? Let's see how the College Football Power Index computer prediction model projects the game.

USC vs. UCLA picks, predictions

College Football Power Index is a computer prediction tool that uses data points from both teams to simulate games 20,000 times and pick straight-up winners.

This week, the model favors USC to hold serve at home, winning out in 75.3 percent of the simulations, or 15,060 of the total projections.

Conversely, the Bruins are expected to win in the remaining 24.7 percent of sims, or the other 4,940 predictions.

By taking the difference between each team's projected scoring margin per game, the computer predicts that USC will defeat UCLA by 7.5 points, enough to cover the line at SI Sportsbook, which names Southern Cal the 7 point favorite.

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UCLA at USC game time

When: Sat., Nov. 18
Time: 12:30 p.m. Pacific
TV: ABC network
Stream live: fuboTV (Try for free)


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James Parks
JAMES PARKS

James Parks is the founder and publisher of College Football HQ. He previously covered football for 247Sports and CBS Interactive. College Football HQ joined the Sports Illustrated Fannation Network in 2022.