College football predictions: ESPN College GameDay hosts make Week 6 game picks
Week 6 of the college football schedule is here, and now it's time to make our final picks and predictions for Saturday's most important games.
There are three matchups on tap featuring AP top 25 ranked teams on the same field, including one surprise game in the Big 12, in addition to one in the SEC, and an intriguing kickoff coming out of the Pac-12.
More college football on SI: College football scores | College football rankings | College football schedule
This week also finds the annual Red River Shootout from the Cotton Bowl pitting Texas and Oklahoma, although the old rivals are down this year, both unranked and at 3-2 coming in.
And there's a major tilt down in the SEC as top-ranked Alabama plays host to Texas A&M in a rematch of last season's major upset and the Aggies looking to avoid a costly third loss on the year.
Here are the final picks from the gang on ESPN College GameDay.
College football predictions: ESPN College GameDay makes final Week 6 game picks
Week 6 college football picks, predictions
Texas vs. Oklahoma. All but one host went with the Longhorns, who return quarterback Quinn Ewers to throw against an ailing Sooner secondary in the Red River Shootout. College Football HQ pick: Texas by 16
Iowa at Illinois. All four analysts siding with the Illini in the Big Ten game up against a stout Hawkeye defense, but an air attack that still hasn't found its footing. College Football HQ pick: Illinois by 6
BYU vs. Notre Dame. An even split between these teams, with BYU coming in ranked at one loss but the unranked 2-2 Irish the slim favorite at the books. College Football HQ pick: Notre Dame by 3
Florida State at NC State. Three of the four pickers went with the Seminoles to upset the Wolfpack on the road behind a powerful rushing attack and dynamic QB play. College Football HQ pick: NC State by 3
Utah at UCLA. Three of four hosts went with UCLA, itself coming off a statement win over Washington and now have a chance to take down the defending Pac-12 champions, themselves already at one loss. College Football HQ pick: Utah by 6
Washington State at USC. Every picker went with the Trojans to defeat the Cougars at home and stay perfect with the Utah game coming up. College Football HQ pick: USC by 17
Tennessee at LSU. The three regular hosts went with Tennessee to stay undefeated on the road at Death Valley, while guest Rob Riggle dissented with a vote for LSU. College Football HQ pick: Tennessee by 4
Arkansas at Mississippi State. A likely injury to quarterback KJ Jefferson moved all but one analyst to pick the Bulldogs today.
Texas A&M at Alabama. Every picker sided with the Crimson Tide to defeat the Aggies at home and stay atop the SEC West.
Kansas State at Iowa State. Two votes each for both teams coming into this Big 12 matchup that finds the Wildcats hoping to stay ranked in the AP top 25 poll
TCU at Kansas. Kirk Herbstreit and Desmond Howard went with the Horned Frogs, while Pat McAfee and guest picker Rob Riggle selected Kansas to stay undefeated. College Football HQ pick: TCU by 2
More from College Football HQ
AP top 25 poll: Alabama overtakes Georgia in college football rankings
College football picks, predictions against the spread for Week 6
Odds, point spreads, betting lines for college football's top games
College football Week 6 games you should watch
Week 6 college football expert picks, predictions
College football rankings: ESPN updates top 25 for Week 6
How to watch college football in the 2022 season
fuboTV provides full, total coverage of the top college football games this season from the major TV networks as well as the SEC Network, Big Ten Network, ACC Network, Pac-12 Network, and others.
Click here to start your free college football fuboTV trial
College football rankings
According to AP top 25 poll
- Alabama
- Georgia
- Ohio State
- Michigan
- Clemson
- USC
- Oklahoma State
- Tennessee
- Ole Miss
- Penn State
- Utah
- Oregon
- Kentucky
- NC State
- Wake Forest
- BYU
- TCU
- UCLA
- Kansas
- Kansas State
- Washington
- Syracuse
- Mississippi State
- Cincinnati
- LSU