Florida vs. Missouri odds, spread, lines: Week 6 college football picks, predictions by computer model

Picks, predictions for Florida vs. Missouri on the Week 6 college football schedule

A pair of SEC East rivals meet in the Swamp as Florida hosts Missouri in college football's Week 6 action on Saturday.

Florida is 3-2 on the year with losses to Kentucky and Tennessee, both ranked SEC rivals, while Mizzou is 7 points from being undefeated in conference play after losing close ones to Auburn and Georgia.

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What do the experts think of the matchup? Let's see how the College Football Power Index computer prediction model projects the game. 

Florida vs. Missouri odds, spread, predictions

Week 6 college football picks: Florida vs. Missouri / USA Today Images

The computer is going with the home team by a large margin, as Florida has the 71.0 percent chance to defeat Missouri on Saturday.

That leaves the Tigers a 29.0 percent shot at taking down the Gators.

The oddsmakers project a somewhat comfortable outing for Florida, which comes into the game as 10.5 point favorites, according to the line at SI Sportsbook, which set the over/under mark at 54 points.

Related: College football odds, betting lines for Week 6

Florida checks in at No. 39 on the index's 131 college football rankings this week after Sunday's defeat over Eastern Washington.

The computer projects UF will win 6.3 games this season and to be 6.8 points better on average than the remaining teams on its schedule.

Missouri moved up 7 spots on the index rankings despite the close loss to Georgia last weekend, but are still second-worst in the SEC with an expected per-game point margin of just plus-2.6 points going forward.

College Football Power Index

Football Power Index (FPI) college football rankings and computer prediction model are a measure of team strength that predicts a team’s future performance.

Rankings and scores predictions are based on 20,000 simulations of a team’s season, using a combination of analytics, including scores to date, quality of opponents, and a team’s schedule.

College football rankings

According to AP top 25 poll

1. Alabama
2. Georgia
3. Ohio State
4. Michigan
5. Clemson
6. USC
7. Oklahoma State
8. Tennessee
9. Ole Miss
10. Penn State
11. Utah
12. Oregon
13. Kentucky
14. NC State
15. Wake Forest
16. BYU
17. TCU
18. UCLA
19. Kansas
20. Kansas State
21. Washington
22. Syracuse
23. Mississippi State
24. Cincinnati
25. LSU

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