Notre Dame vs. Marshall odds, spread, line: Week 2 college football picks, predictions by computer model

College Football Power Index picks, predictions for Notre Dame vs. Marshall

Notre Dame played hard at Ohio State, but couldn't overcome a scoreless second half to start the 2022 football season off 0-1.

That doesn't spell doom for the Irish's College Football Playoff hopes, though, provided it can stay just about perfect the rest of the way.

Up next in that campaign is the home opener against Marshall under the watchful eyes of Touchdown Jesus. 

What do the experts think of the matchup? Let's see how the College Football Power Index computer prediction model projects the game.

Notre Dame vs. Marshall odds, spread, line, predictions

Notre Dame hosts Marshall on Week 2 of the college football schedule

Football Power Index is going with the Fighting Irish, who have an 88.8 percent chance to defeat Marshall in Marcus Freeman's home opener.

By contrast, the Herd have an 11.2 percent shot to upset the Irish.

Oddsmakers are also going with Notre Dame, which comes into the matchup as 20.5 point favorites, according to SI Sportsbook, which set the over/under mark at 51.5 points.

FPI rates Notre Dame as the No. 6 team in its latest college football rankings and projects it as 17.8 points better on average than every team on its schedule.

The index predicts ND will win 8.7 games this season and has a 17.7 percent chance to make the College Football Playoff.

AP top 25 voters named Notre Dame the No. 8 team in the latest Week 2 poll, a drop of 3 spots after last weekend's loss at Ohio State.

College Football Power Index

ESPN Football Power Index (FPI) college football rankings and computer prediction model are a measure of team strength that predicts a team’s future performance. 

Rankings and scores predictions are based on 20,000 simulations of a team’s season, using a combination of analytics, including scores to date, quality of opponents, and a team’s schedule.

College football rankings

According to the AP top 25 poll

1. Alabama
2. Georgia
3. Ohio State
4. Michigan
5. Clemson
6. Texas A&M
7. Oklahoma
8. Notre Dame
9. Baylor
10. USC
11. Oklahoma State
12. Florida
13. Utah
14. Michigan State
15. Miami
16. Arkansas
17. Pittsburgh
18. NC State
19. Wisconsin
20. Kentucky
21. BYU
22. Ole Miss
23. Wake Forest
24. Tennessee
25. Houston

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