College football picks against the spread for Week 3 games

Heading into the Week 3 college football schedule, we lock in our picks against the spread for the top games this weekend.
College football Week 3 picks against the spread
College football Week 3 picks against the spread / USA Today Sports | Imagn

There’s more competition than ever for the national championship after the College Football Playoff expanded to 12 teams, meaning that early season games don’t mean quite as much as before, but the Week 3 schedule presents what could be some sneakily impactful matchups. With that in mind, let’s lock in our picks against the spread.

How are we doing? College Football HQ went 4-5 against the spread last week, bringing our total for the year at 6-8 in our ATS predictions.

College football picks against the spread for Week 3 games

Lines are courtesy of FanDuel Sportsbook

Texas A&M at Florida

ATS pick: Florida +3.5 ... Two teams a combined 0-4 against the spread this year, and while neither boast the kind of skill threats you find across the SEC, they each play good football on the lines. While the Aggies’ D-line is better, the Gators have a slight edge moving the ball.

... Florida by 4

More ... Florida vs. Texas A&M prediction

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UTSA at Texas

ATS pick: UTSA +33.5 ... That’s a big line against a team that’s won two league titles the last three years and could be an overreaction to Texas’ big win at Michigan last week. Still, there’s no doubt the Longhorns are the far superior side and UTSA has taken a step back, but Texas could elect to rest starters to stay healthy ahead of their SEC debut.

... Texas by 31

More ... Texas vs. UTSA score prediction

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Tulane at Oklahoma

ATS pick: Tulane +13.5 ... The Green Wave blew a chance to upset a ranked Kansas State last week despite a solid offensive effort, but its vulnerable pass defense could provide an avenue for redemption for an OU attack that can exploit passing gaps downfield. Still, there’s concern the Sooners after a close call against lowly Houston, and they could be caught looking ahead to hosting Tennessee next week in the SEC opener.

... Oklahoma by 10

More ... Oklahoma vs. Tulane score prediction

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Boston College at Missouri

ATS pick: Missouri -16.5 ... BC has the firepower to test Mizzou’s defense especially on the ground and can play some good run defense, but the Tigers have the decided edge at wide receiver and have been playing elite defense all over the field.

... Missouri by 17

More ... Missouri vs. Boston College prediction

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Oregon at Oregon State

ATS pick: Oregon State +16.5 ... The Ducks are 0-2 against the spread this year and have played too close for comfort, winning by a combined 13 points with questions along the lines of scrimmage that were meant to be a team strength. OSU is 5th in rushing and playing at home. We’ll wait to pick Oregon until it proves worthy.

... Oregon by 7

More ... Oregon vs. Oregon State score prediction

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Georgia at Kentucky

ATS pick: Georgia -22.5 ... Kentucky has some bodies who can get pressure, but the Bulldogs still have too much variety at the skill positions, and after watching South Carolina play good defense up front against this team, Georgia’s far superior pass rush will look that much better.

... Georgia by 28

More ... Georgia vs. Kentucky prediction

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Notre Dame at Purdue

ATS pick: Purdue +7.5 ... The Irish offense has shifted into neutral under Riley Leonard’s tutelage, and while the Boilermaker defense may prove more generous than others, Hudson Card still has the arm to keep this closer than Marcus Freeman would hope.

... Notre Dame by 6

More ... Notre Dame vs. Purdue score prediction

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Alabama at Wisconsin

ATS pick: Alabama -16.5 ... Tyler Van Dyke could get some good shots early on against a young Bama secondary and playing with his home crowd egging him on, and the Tide could struggle protecting its quarterback again, but SEC speed kills, until proven otherwise.

... Alabama by 21

More ... Alabama vs. Wisconsin prediction

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LSU at South Carolina

ATS pick: South Carolina +6.5 ... The Gamecocks have ably rushed the passer through 2 games, but they’ll run into a more formidable obstacle in LSU’s superb offensive line, especially at both tackle positions. And while the Tigers may have trouble running the ball, Garrett Nussmeier should make up for it by throwing some good receivers against a susceptible Carolina secondary.

... LSU by 6

More ... LSU vs. South Carolina prediction

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Game odds refresh periodically and are subject to change

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James Parks

JAMES PARKS

James Parks is the founder and publisher of College Football HQ. He previously covered football for 247Sports and CBS Interactive. College Football HQ joined the Sports Illustrated Fannation Network in 2022.