College football picks against the spread for Week 8 games

Looking ahead to an active Week 8 college football schedule, let's lock in our picks against the spread for the most important games.

As we look ahead to an active Week 8 college football schedule across the country full of impactful games, let’s lock in our final picks against the spread for the most important games on Saturday.

How are we doing? College Football HQ went 6-4 in our picks against the spread last weekend, bringing our 2024 season record to 27-34 overall.

For better or worse, here are the picks we’re making against the spread for college football’s biggest games on the Week 8 schedule on Saturday.

College football picks against the spread for Week 8 games

Lines are courtesy of FanDuel Sportsbook

Nebraska at Indiana

College football Week 8 picks against the spread / Marc Lebryk-Imagn Images

ATS pick: Nebraska +6.5 | While the Hoosiers’ offense has been putting up serious points, ranking 6th nationally in yards per play, they haven’t been tested by a defense of Nebraska’s caliber, especially in the front seven, but the Cornhuskers’ sketchy offense prevents us from picking the upset outright.

... Indiana by 3

• Nebraska vs. Indiana prediction
• Score prediction by expert model

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Miami at Louisville

College football Week 8 picks against the spread / Matt Pendleton-Imagn Images

ATS pick: Louisville +4.5 | Miami has been tested in recent outings, and Louisville is playing some of the ACC’s best defense up front right now and will credibly test Cam Ward’s ability to get whatever he wants, while the Cardinals have the skill threats to get on the board with ease.

... Miami by 3

• Miami vs. Louisville score prediction

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Auburn at Missouri

College football Week 8 picks against the spread / John Reed-Imagn Images

ATS pick: Missouri -3.5 | Mizzou isn’t great at generating takeaways, a key fact that could aid Auburn’s offense and keep this close, but Hugh Freeze’s team averages all of 16 points in SEC games so far this season. Missouri can do better than that.

... Missouri by 7

• Auburn vs. Missouri prediction

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East Carolina at Army

College football Week 8 picks against the spread / Danny Wild-Imagn Images

ATS pick: Army -16.5 | While the Pirates have won the last 8 overall in this series, they just surrendered over 300 yards rushing against Charlotte, which is 107th nationally in that category, and goes against an Army behemoth that is No. 1 in FBS in rushing output.

... Army by 20

• Army vs. East Carolina score prediction

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Notre Dame at Georgia Tech

College football Week 8 picks against the spread / Matt Cashore-Imagn Images

ATS pick: Notre Dame -9.5 | Haynes King likely won’t play, depriving Tech its starting quarterback and a principal rushing threat, and taking a huge burden off the Irish defense as it looks to contain the ACC’s most productive ground game.

... Notre Dame by 11

• Notre Dame vs. Georgia Tech prediction
• Score prediction by expert model

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Michigan at Illinois

College football Week 8 picks against the spread / Junfu Han / USA TODAY NETWORK

ATS pick: Illinois +3.5 | Michigan is still a favorite despite the almost complete absence of a passing game. Such is the reputation of its rushing offense and defensive front seven, and while the Wolverines will rattle Luke Altmyer a little behind a shaky line, the Illinois receivers could be the difference in this marquee home game.

... Illinois by 3

• Michigan vs. Illinois prediction
• Score prediction by expert model

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LSU at Arkansas

College football Week 8 picks against the spread / Scott Kinser-Imagn Images

ATS pick: LSU -2.5 | Garrett Nussmeier commands one of the nation’s most productive passing attacks and he’s working behind one of the best offensive lines, too. That could be enough to make up for a defense that will let the Razorbacks get some momentum on the ground and could sneak a few passes behind its secondary.

... LSU by 4

• LSU vs. Arkansas prediction
• Score prediction by expert model

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Alabama at Tennessee

College football Week 8 picks against the spread / Randy Sartin-Imagn Images

ATS pick: Tennessee +3.5 | There’s growing concern around the Vols’ ability to move the ball in the air consistently, although Alabama’s secondary could prove a little more generous, but it’s up to Tennessee’s strong front seven to stop, and its rushing attack to match, the Tide’s big-play skill threats.

... Alabama by 3

• Alabama vs. Tennessee prediction
• Score prediction by expert model

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Georgia at Texas

College football Week 8 picks against the spread / Dale Zanine-Imagn Images

ATS pick: Georgia +4.5 | A second loss in SEC play could put Georgia out of the playoff, an inconceivable thought given its recent dominance, but there are relative declines along this pass rush and in the secondary that play into the Longhorns’ offensive strengths, even if Carson Beck and the Bulldog receivers have the potential to keep this close.

... Texas by 3

• Georgia vs. Texas prediction
• Score prediction by expert model

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Game odds refresh periodically and are subject to change.

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