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Philadelphia Eagles quarterback Jalen Hurts has led his team to a 6-1 ATS record on the road.

NFL Best Bets for Week 16 (Predictions for Eagles vs. Commanders, Giants vs. Falcons)

Philadelphia Eagles quarterback Jalen Hurts has led his team to a 6-1 ATS record on the road.

NFL Best Bets for Week 16 (Predictions for Eagles vs. Commanders, Giants vs. Falcons)

The Sports Illustrated Betting team shares their favorite bets on the board for Week 16 of the 2024 NFL season.

RECENT STORIES

Nov 16, 2024; San Jose, California, USA; San Jose State Spartans wide receiver Nick Nash (3) reacts after making a catch for a first down against the Boise State Broncos in the third quarter at CEFCU Stadium. Mandatory Credit: Cary Edmondson-Imagn Images

South Florida vs San Jose State Prediction, Odds and Key Players for Hawai'i Bowl

Nov 23, 2024; Columbia, South Carolina, USA; South Carolina Gamecocks quarterback LaNorris Sellers (16) scrambles against the Wofford Terriers in the first quarter at Williams-Brice Stadium. Mandatory Credit: Jeff Blake-Imagn Images

South Carolina vs. Illinois Prediction, Odds and Key Players for Citrus Bowl

Dec 16, 2024; Minneapolis, Minnesota, USA; Minnesota Vikings quarterback Sam Darnold (14) passes the ball against the Chicago Bears in the fourth quarter at U.S. Bank Stadium. Mandatory Credit: Brad Rempel-Imagn Images

Vikings vs. Seahawks Best NFL Prop Bets and Anytime Touchdown Scorer Picks for NFL Week 16 (Fade Sam Darnold?)

Bet on Jauan Jennings to have a big game against the Dolphins in Week 16.

49ers vs. Dolphins Best NFL Prop Bets and Anytime Touchdown Scorer Picks for NFL Week 16

Notre Dame running back Jeremiyah Love (4) and quarterback Riley Leonard (13) celebrate a Love touchdown during the first round of the College Football Playoff between Notre Dame and Indiana at Notre Dame Stadium on Friday, Dec. 20, 2024, in South Bend.

Notre Dame National Championship Odds Update, Open as Favorite Against Georgia in Sugar Bowl

Continue to fade Anthony Richardson in Week 16 against the Titans.

Titans vs. Colts Best NFL Prop Bets and Anytime Touchdown Scorer Picks for NFL Week 16

Jerome Ford could have a big performance against the Bengals in Week 16.

Browns vs. Bengals Best NFL Prop Bets and Anytime Touchdown Scorer Picks for NFL Week 16 (Believe in Jerome Ford)

Tottenham vs. Liverpool Prediction, Odds, and Best Bets for Premier League Week 17

Saquon Barkley is primed for another big performance against the Commanders.

Eagles vs. Commanders Best NFL Prop Bets and Anytime Touchdown Scorer Picks for NFL Week 16

Arizona Cardinals running back James Conner is a great bet to find the end zone in Week 16.

Cardinals vs. Panthers Best NFL Prop Bets and Anytime Touchdown Scorer Picks for NFL Week 16

Pittsburgh Steelers head coach Mike Tomlin is elite against the spread as an underdog.

Best NFL Picks and Predictions Today (How to Bet Steelers vs. Ravens on Saturday in NFL Week 16)

Caleb Williams has a chance to thrive against a banged-up Lions defense.

Lions vs. Bears Best NFL Prop Bets and Anytime Touchdown Scorer Picks for NFL Week 16 (Believe in Caleb Williams)

Baltimore Ravens wide receiver Diontae Johnson.

Is Diontae Johnson Playing Today? (Injury Update, Betting Impact for Steelers vs. Ravens)

Can Puka Nacua's hot streak continue in Week 16?

Rams vs. Jets Best NFL Prop Bets and Anytime Touchdown Scorer Picks for NFL Week 16

Houston Texans running back Joe Mixon.

Is Joe Mixon Playing Today? (Injury Update, Betting Impact for Texans vs. Chiefs)

Pittsburgh Steelers wide receiver George Pickens.

Is George Pickens Playing Today? (Injury Update, Betting Impact for Steelers vs. Ravens)

Chiefs wide receiver Marquise Brown.

Is Marquise Brown Playing Today? (Injury Update, Betting Impact for Texans vs. Chiefs)

Kansas City Chiefs running back Isiah Pacheco is a great prop target this week.

Best NFL Picks and Predictions Today (How to Bet Texans vs. Chiefs on Saturday in NFL Week 16)

Kansas City Chiefs quarterback Patrick Mahomes.

Is Patrick Mahomes Playing Today? (Injury Update, Betting Impact for Texans vs. Chiefs)

Dec 18, 2024; Milwaukee, Wisconsin, USA; Marquette Golden Eagles guard Kam Jones (1) drives for the basket against Butler Bulldogs guard Finley Bizjack (13) during the second half at Fiserv Forum. Mandatory Credit: Jeff Hanisch-Imagn Images

Marquette vs. Xavier Prediction, Odds and Key Players for Saturday, December 21

Dec 14, 2024; Lexington, Kentucky, USA; Kentucky Wildcats guard Lamont Butler (1) smiles during the second half against the Louisville Cardinals at Rupp Arena at Central Bank Center. Mandatory Credit: Jordan Prather-Imagn Images

Ohio State vs. Kentucky Prediction, Odds and Key Players for Saturday, December 21

Memphis' Tyrese Hunter (11) looks to pass the ball during the game between Arkansas State University and the University of Memphis at FedExForum in Memphis, Tenn., on Sunday, December 8, 2024.

Mississippi State vs. Memphis Prediction, Odds and Key Players for Saturday, December 21

Dec 17, 2024; Los Angeles, California, USA; UCLA Bruins forward William Kyle III (24) dunks the ball against Prairie View A&M Panthers in the second half at Pauley Pavilion presented by Wescom. Mandatory Credit: Kirby Lee-Imagn Images

UCLA vs. North Carolina Prediction, Odds and Key Players for Saturday, December 21

Nov 19, 2024; Milwaukee, Wisconsin, USA; Purdue Boilermakers guard Braden Smith (3) during the game against the Marquette Golden Eagles at Fiserv Forum. Mandatory Credit: Jeff Hanisch-Imagn Images

Purdue vs. Auburn Prediction, Odds and Key Players for Saturday, December 21