2021 Wyndham Championship: Latest Betting Odds, Favorites and Sleeper Picks for Sedgefield Country Club

North Carolina native Webb Simpson leads the way as he looks to make his mark on the 2021 PGA Tour season.

It might be cliché, but there may be no better sport to perfectly sum up, “it’s not how you start, it’s how you finish.”

For leaders heading into the final round of the WGC-FedEx St. Jude Invitational, especially prospective wire-to-wire winner Harris English, they’ll be left wondering what could have been. Inconsistent play and risky decisions (looking at you Cam Smith) allowed pressure-free rounds of 63 and 64 by Hideki Matsuyama and Sam Burns, respectively, to join Abraham Ancer in a playoff. And in the end, it was Ancer, who’s been on the precipice of glory for a few years now, finally capturing the first PGA Tour victory of his career.

As for the picks, we are beginning to feel like Louis Oosthuizen with all these close calls to the winner’s circle. Both Smith and Dustin Johnson secured top-10 finishes for us and after a promising start, our sleeper, Max Homa, could not get anything going on the weekend.

The final week prior to the FedEx Cup Playoffs is upon us with the Wyndham Championship at Sedgefield Country Club in Greensboro, N.C. Many of the world’s top players will be resting for the beginning of the playoffs, so it is a golden opportunity for those players looking to sneak into the top-125 of the FedEx Cup standings. The last five champions have been at least 20-under par, so riding the birdie train will be imperative to contend.

According to William Hill, North Carolina native Webb Simpson is the favorite at 12-1. Next up is Matsuyama, who is coming off his excruciating lip-out on the first playoff hole at last week’s St. Jude Invitational, at 14-1. To follow is the highest-ranked player in the field -- Oosthuizen at 18-1. To close out the notables is Patrick Reed at 22-1.

For our favorite, we’re going against the grain and taking the chalk with Simpson. There is certainly no value here, but it’s too hard to ignore the history of this man at Sedgefield, and his home state in general. Over the last four years, Simpson has finished either second or third at the Wyndham Championship, the site of his first win on Tour in 2011. He looked pedestrian for most of his week in Memphis, but fired a final-round 65 to carry some momentum into a tournament he loves so much that he named one of his daughters after it.

For a midrange pick, Kevin Kisner at 33-1 looks good. Another low-country native, Kisner finished T-3 at the Wyndham Championship last year and had success in 2014 and 2016 with a pair of top-10s. In his last 12 rounds at this course, Kisner is fourth in strokes gained (total) and throughout 2021 on Tour, he’s 14th in strokes gained (putting). In his most recent four starts, he’s finished in the top-10 twice, so look for Kisner to be very comfortable this week at Sedgefield.

For a sleeper, Patton Kizzire at 66-1 is a solid value play. Over his last ten events, he’s made seven cuts which includes two top-5s and an 11th-place finish. Kizzire is a guy who does everything well, so it’s only a matter of time before he puts it all together. In two relevant strokes gained categories for Sedgefield, birdie or better and putting (Bermuda greens), he ranks first and third over his past 24 rounds played. Kizzire should not find too much trouble this week, so look for him to be in contention the whole way through.

2021 picks scoreboard:

Winners: 3
Top 10s: 19
Top 20s: 12
Misses: 51

Here are some notable odds, according to William Hill:

Webb Simpson 12-1

Hideki Matsuyama 14-1

Louis Oosthuizen 18-1

Patrick Reed 22-1

Brian Harman 28-1

Will Zalatoris 28-1

Jason Kokrak 28-1

Sungjae Im 30-1

Kevin Kisner 33-1

Tommy Fleetwood 33-1

Charl Schwartzel 33-1

Russell Henley 35-1

Matthew Wolff 40-1

Kevin Streelman 40-1

Seamus Power 40-1

Kevin Na 40-1

Si-Woo Kim 40-1

Gary Woodland 40-1

Bubba Watson 40-1

Adam Scott 40-1

Rickie Fowler 45-1

Justin Rose 45-1

Robert MacIntyre 45-1

Brandt Snedeker 45-1

Sebastian Munoz 50-1

Branden Grace 50-1

Jhonattan Vegas 50-1

J.T. Poston 50-1

Erik Van Rooyen 50-1

Mito Pereira 50-1

Zach Johnson 55-1

Talor Gooch 55-1

Ryan Moore 60-1

Harold Varner 60-1

Patton Kizzire 66-1

Lucas Glover 66-1

Chez Reavie 66-1

Doug Ghim 66-1

Hank Lebioda 66-1

MacKenzie Hughes 70-1

Ryan Armour 80-1

Luke List 80-1

Doc Redman 80-1

Brendon Todd 80-1

Chris Kirk 80-1

Lanto Griffin 80-1

Rory Sabbatini 80-1

Adam Schenk 80-1

C.T. Pan 80-1

Joel Dahmen 80-1

Keith Mitchell 100-1

Patrick Rodgers 100-1

Kramer Hickok 100-1

Kyle Stanley 100-1

Adam Hadwin 100-1

Matt Jones 100-1

Jim Herman 100-1

Mark Hubbard 100-1

Dylan Frittelli 100-1

Andrew Putnam 100-1

Bo Hoag 100-1

Roger Sloan 100-1

Scott Piercy 100-1

Francesco Molinari 100-1

Tom Lewis 100-1

Brandon Hagy 100-1

Henrik Norlander 125-1

Adam Long 125-1

Scott Stallings 125-1

Matt Kuchar 125-1

Kyoung-Hoon Lee 125-1

Michael Thompson 125-1

Sepp Straka 125-1

Brian Stuard 125-1

Aaron Wise 125-1

Sam Ryder 150-1

Byeong Hun An 150-1

Brice Garnett 150-1

Richy Werenski 150-1

Martin Laird 150-1

Joseph Bramlett 150-1

Jason Dufner 200-1

Camilo Villegas 200-1

Matthew NeSmith 200-1

Nick Taylor 200-1

Wyndham Clark 200-1

Vincent Whaley 200-1

James Hahn 200-1

Russell Knox 200-1

Beau Hossler 200-1

Anirban Lahiri 200-1

Satoshi Kodaira 200-1