NFL Odds: Seahawks big favorites over Rams in a Week 15 full of divisional matchups

The Seahawks are big favorites over the Rams in a Week 15 that's full of divisional matchups.

Meetings between divisional opponents highlight the NFL betting opportunities of Week 15. And the Seattle Seahawks (8-4-1) may have the easiest matchup of any as they attempt to clinch the NFC West on Thursday night.

The Seahawks are massive 14-point home favorites on the NFL point spreads as they host the Los Angeles Rams (4-­9) at sportsbooks monitored by OddsShark.com.

The Rams fired head coach Jeff Fisher on Monday and replaced him on an interim basis with special-teams coordinator John Fassel, who will have his work cut out for him. That is because Seattle has won 17 of the last 23 meetings straight up, according to the OddsShark NFL Database.

The Seahawks, who were routed 38–10 by the Green Bay Packers last week, are also 7–0 straight up and 5–1–1 against the spread in their previous seven games coming off a loss.

NFL Week 14 Blanket: Why Seahawks may be doomed without Earl Thomas

On Saturday, the Miami Dolphins (8–5) continue their run for an AFC Wild Card berth, which they’ll now have to do without starting quarterback Ryan Tannehill, when they visit the New York Jets (4–9) as 2.5-point road favorites at the sportsbooks.

Tannehill suffered ACL and MCL sprains in his left knee in last week’s 26–23 victory against the Arizona Cardinals. Matt Moore will start in his place and hopes to lead the Dolphins to their seventh win in nine meetings with the Jets away from home.

However, Miami has a record of only 1–12 against the spread in its last 13 December games.

Q&A: Ravens S Eric Weddle on how Brady, Pats cracked Baltimore's vaunted defense

There are four more key divisional games Sunday, including the Packers (7–6) at the Chicago Bears (3–10), the Jacksonville Jaguars (2–11) at the Houston Texans (7–6), the Pittsburgh Steelers (8–5) at the Cincinnati Bengals (5–7–1), and the Oakland Raiders (10–3) at the San Diego Chargers (5–8).

Green Bay (-6.5), Pittsburgh (-3.5) and Oakland (-2.5) are all road favorites while Houston (-6) is home chalk and will be going for its sixth straight win over Jacksonville while trying to extend its winning streak versus AFC South opponents to 10.

The Texans are also an impressive 8–0–1 against the spread in their last nine divisional matchups.