Sunday Roundup: Who to Bet on in Every NFL Week 11 Afternoon Game

In the Colts and Texans, the AFC South features two of Week 11's best bets against the spread.

The Chiefs-Rams tilt on Monday night is the Week 11 headliner, but Sunday's slate features plenty of intriguing contests, too. Here are your betting plays for the afternoon games.

Carolina Panthers (-4.5) at Detroit Lions

1:00 p.m. ET

• Carolina is 2-8-1 against the spread over its past 11 games as a road favorite.

• Over the total is 3-0 in games Detroit has played at home against Carolina since the start of the 2005 season.

• NFL road teams are 0-4 against the spread when coming off a road loss since the start of this month.

Side: Lions (+4.5)

Confidence Level: Moderate (on a scale of Low/Moderate/High/Very High/Extremely High)

Total: Over 49.5

Confidence Level: Moderate

Dallas Cowboys at Atlanta Falcons (-3)

1:00 p.m.

• Dallas is 10-2 against the spread when coming off a game in which the team gained 400 or more total yards since the start of the 2016.

• Over the total is 15-7 in games Atlanta has played as a home favorite since the start of the 2016 season.

• Atlanta was gashed for 211 rushing yards by Cleveland last Sunday, and the Dallas run game presents a more formidable challenge than what the Falcons saw in Cleveland.

Side: Cowboys (+3)

Confidence Level: Low

Total: Over 49.5

Confidence Level: Moderate

Tennessee Titans at Indianapolis Colts (-1.5)

1:00 p.m.

• Indianapolis is 8-2 against the spread in home games played against Tennessee since the start of the 2008 season.

• Under the total is 7-3 in games Tennessee has played on the road against Indianapolis since the start of the 2008 season.

• Colts quarterback Andrew Luck is 9-0 straight up and 8-1 against the spread when facing the Titans in his career.

Side: Colts (-1.5)

Confidence Level: Very High

Total: Over 51

Confidence Level: Very High

Houston Texans (-3) at Washington Redskins

1:00 p.m.

• Houston is 4-0 against the spread under head coach Bill O’Brien when coming off a bye week.

• Under the total is 10-4 in games Houston has played following a bye week since 2004.

• The big mismatch in this one would appear to be Houston’s front seven against a Redskins offensive line that’s been decimated by injuries with left tackle Trent Williams out along with starting guards Brandon Scherff and Shawn Lauvao.

Side: Texans (-3)

Confidence Level: Extremely High

Total: Under 42

Confidence Level: Moderate

Tampa Bay Buccaneers at New York Giants (-2.5)

1:00 p.m.

• The road team is 4-0 against the spread in games the Giants have played against Tampa Bay since 2008.

• Under the total is 24-6 past the midway point of the season since the start of 2014 when the home team has a win percentage of less than or equal to 25% and the road has a losing record.

• The Giants are 2-9 against the spread since the start of last season in games in which the spread is between +3 and -3.

Side: Buccaneers (+2.5)

Confidence Level: Low

Total: Under 52.5

Confidence Level: Very High

Pittsburgh Steelers (-5) at Jacksonville Jaguars

1:00 p.m.

• Jacksonville is 8-3 against the spread in games played against Pittsburgh since the start of the 2002 season.

• Under the total is 11-2 in games Pittsburgh has played after a win by 14 or more points under head coach Mike Tomlin.

• The Jaguars are 8-0 against the spread when facing an AFC North opponent over the past four calendar years.

Side: Jaguars (+5)

Confidence Level: Moderate

Total: Under 46.5

Confidence Level: High

Denver Broncos at Los Angeles Chargers (-7)

4:05 p.m.

• Denver is 5-2 against the spread in road games played against the Chargers since the start of the 2011 season.

• Under the total is 5-0 in games Denver has played on the road against the Chargers since the start of the 2013 season.

• The Chargers have averaged just 17 points per game versus the Broncos since the start of the 2014 season.

Side: Broncos (+7)

Confidence Level: High

Total: Under 46

Confidence Level: Extremely High

Oakland Raiders at Arizona Cardinals (-5.5)

4:05 p.m.

• Arizona is 5-9 against the spread when facing an AFC team since the start of the 2015 season.

• Under the total is 7-0 in games Oakland has played against NFC teams since the start of last season.

• The Cardinals are 1-4 at home this season (having beaten only the 49ers) with a point differential of -55.

Side: Raiders (+5.5)

Confidence Level: Low

Total: Under 41

Confidence Level: High

Philadelphia Eagles at New Orleans Saints (-7.5)

4:25 p.m.

• New Orleans is 9-2 against the spread following three or more consecutive wins since the start of last season.

• Over the total is 7-1 in games Philadelphia has played as a road underdog under head coach Doug Pederson.

• The Eagles are 0-3 (against the spread and straight up) this season versus teams that currently have winning records.

Side: Saints (-7.5)

Confidence Level: Moderate

Total: Over 56.5

Confidence Level: High