49ers LT Trent Williams Seems Unlikely to Play Against the Bills

It seems like Trent Williams will miss his second game in a row this weekend with an ankle injury.
Sep 29, 2024; Santa Clara, California, USA; San Francisco 49ers offensive tackle Trent Williams (71) blocks against New England Patriots defensive end Deatrich Wise Jr. (91) during the second quarter at Levi's Stadium. Mandatory Credit: Sergio Estrada-Imagn Images
Sep 29, 2024; Santa Clara, California, USA; San Francisco 49ers offensive tackle Trent Williams (71) blocks against New England Patriots defensive end Deatrich Wise Jr. (91) during the second quarter at Levi's Stadium. Mandatory Credit: Sergio Estrada-Imagn Images / Sergio Estrada-Imagn Images
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It seems like Trent Williams will miss his second game in a row this weekend with an ankle injury.

Williams didn't practice on Wednesday. And in the locker room, he was seen using a knee scooter, which means his knee was resting on a scooter while his injured ankle was elevated off the ground. Which means he doesn't want to put any weight on it.

Williams injured his ankle a few weeks ago in the 49ers' 23-20 win over the Tampa Bay Buccaneers. The next week, Williams took a Toradol shot and played in the 49ers' 20-17 loss to the Seattle Seahawks. He must have made his injury worse in that game considering he didn't play this past Sunday in the 49ers' 38-10 loss to the Packers and now he's using a knee scooter to get around the facility.

Williams, 36, hasn't played a full season since 2013. He typically misses a game or two every season. So if history predicts the future, it's possible he could return when the 49ers return from Buffalo. Their next two games will be at home and they'll be winnable -- the 49ers will face the Bears and the Rams, two teams that are mediocre at best.

This offseason, the 49ers renegotiated Williams' contract and gave him a $25.69 million signing bonus after he skipped all of OTAs, minicamp and training camp. He's under contract through 2026 when he'll be 38. He currently is the fifth-highest-graded offensive tackle in the NFL according to Pro Football Focus.

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Grant Cohn
GRANT COHN

Grant Cohn has covered the San Francisco 49ers daily since 2011. He spent the first nine years of his career with the Santa Rosa Press Democrat where he wrote the Inside the 49ers blog and covered famous coaches and athletes such as Jim Harbaugh, Colin Kaepernick and Patrick Willis. In 2012, Inside the 49ers won Sports Blog of the Year from the Peninsula Press Club. In 2020, Cohn joined FanNation and began writing All49ers. In addition, he created a YouTube channel which has become the go-to place on YouTube to consume 49ers content. Cohn's channel typically generates roughly 3.5 million viewers per month, while the 49ers' official YouTube channel generates roughly 1.5 million viewers per month. Cohn live streams almost every day and posts videos hourly during the football season. Cohn is committed to asking the questions that 49ers fans want answered, and providing the most honest and interactive coverage in the country. His loyalty is to the reader and the viewer, not the team or any player or coach. Cohn is a new-age multimedia journalist with an old-school mentality, because his father is Lowell Cohn, the legendary sports columnist for the San Francisco Chronicle from 1979 to 1993. The two have a live podcast every Tuesday. Grant Cohn grew up in Oakland and studied English Literature at UCLA from 2006 to 2010. He currently lives in Oakland with his wife.