Titans vs. Bills Betting Odds: How Much is Buffalo Favored on Monday Night Football?

The Bills enter the week favored to beat the Titans.
Andrew Nelles / Tennessean.com / USA TODAY NETWORK

The Buffalo Bills (1-0) are preparing to host the Tennessee Titans (0-1) on Monday Night Football this week, and even though both teams won their respective divisions last season and lost in the AFC Divisional Round, the two teams took different paths in Week 1.

The Bills cruised to a Week 1 road victory against the defending champion Los Angeles Rams, while the Titans struggled and fell to the lowly New York Giants at home.

Week 1's results have shifted the betting odds for the week. Caesar's Sportsbook has the Rams tabbed as a 10-point favorite with six days before the game. Here's what CBS Sports wrote about the opening line ...

Buffalo's advantage has increased by two points, making them now a 10-point favorite in this Monday night matchup. The Bills looked every bit the part of a Super Bowl favorite in their blowout win over the Rams in the opener and

Josh Allen

looked like a legit MVP candidate. On the other side, Tennessee was just upset by the Giants in a game where they had no answer for Saquon Barkley. Even

Derrick Henry

wasn't his usual self, averaging just 3.9 yards per carry. 

The Titans are 3-7 ATS in their last 10 games overall and are not facing a Bills team that has plenty of rest after playing last Thursday. Buffalo is also 5-1-1 in their last seven games and 3-0-1 ATS at home. 

The Titans were the AFC's No. 1 seed last season, so it's hard to see them as such an underdog so early in this season ... but the betting line may be more of a testament as to how strong the Bills looked in their first game.

The Bills were the only team apart from the Kansas City Chiefs to win their first game by more than three scores, and it appears Las Vegas expects them to win by multiple scores for the second week in a row.

The Bills and Titans face off at Highmark Stadium in Buffalo Monday at 7:15 p.m.

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Jeremy Brener
JEREMY BRENER

Jeremy Brener is an editor, writer and social media manager for several Fan Nation websites. His work has also been featured in 247 Sports and SB Nation as a writer and podcaster. Brener has been with Fan Nation since 2021. Brener grew up in Houston, going to Astros, Rockets and Texans games as a kid. He moved to Orlando in 2016 to go to college and pursue a degree. He hosts "The Dream Take" podcast covering the Rockets, which has produced over 350 episodes since March 2020. Brener graduated in May 2020 from the University of Central Florida with a Bachelor's degree in Broadcast Journalism minoring in Sport Business Management. While at UCF, Brener worked for the school's newspaper NSM.today and "Hitting the Field," a student-run sports talk show and network. He was the executive producer for "Hitting the Field" from 2019-20. During his professional career, Brener has covered a number of major sporting events including the Pro Bowl, March Madness and several NBA and NFL games. As a fan, Brener has been to the 2005 World Series, 2010 FIFA World Cup and the 2016 NCAA National Championship between the Villanova Wildcats and North Carolina Tar Heels. Now, Brener still resides in the Central Florida area and enjoys writing, watching TV, hanging out with friends and going to the gym. Brener can be followed on Twitter @JeremyBrener. For more inquiries, please email jeremybrenerchs@gmail.com.