Diablo 4: how to beat Duriel in Act VI

Our guide here will tell you everything you need to know to defeat Duriel in Diablo 4

Act VI marks the end of Diablo 4’s campaign, but it’s still long and packed with tough boss fights. In fact, Act VI has the highest concentration of big bosses to fight in the entire game, and it’ll ultimately prove to be the most challenging Act over the course of the story.

Reading our guides to Astaroth, Brol, Andariel, Elias, and Uznu might give you an idea of what to expect here, but you should make sure you’re fully prepared before diving into the battles ahead. But don’t worry — our guide here will tell you everything you need to know to defeat Duriel in Diablo 4’s Act VI. You’re welcome.

Make sure you check out our tips and tricks for Diablo 4, as they can help you get through tough boss fights like this one without too much trouble. If you’re thinking of trying again with a different class, you should also take a look at what we think is the best starting class in Diablo 4.

How to beat Duriel – Diablo 4 boss guide

Duriel has one richest and most varied movesets in the entire Diablo 4, so there’s a chance that after just playing the story campaign you might not feel properly prepared for the task ahead. If you find yourself struggling, it can be worth taking on some of the extra side quests you’ve put off until now, to get yourself some extra levels and hopefully some better gear.

Duriel can do the following in combat:

• Descend underground and rise up again, striking you on the way out of the ground
• Melee attack with his two claws
• Catch you in his jaws, dealing great damage
• Throw bullets at you from his stomach

You should definitely stay as far away from Duriel as possible, although the boss room is full of obstacles and you might not always be able to do so. He’ll chase you all over the arena for melee attacks, which are undoubtedly the most fearsome and hit for huge damage.

Further complicating the encounter is the boss’ health bar, which has only two sections. This means you’ll have less chance of recovering your own health using his health potion drops, so potion management and avoiding taking damage as best you can should be a key part of your strategy.

Something you might not immediately notice is that you can heal yourself with potions even while in Duriel’s stomach, so if you get gobbled up, don’t give up hope. Most other attacks are reasonably avoidable, as long as you time your dodges well and stay away when you can.

Follow our advice above, and you will succeed in defeating Duriel in Diablo 4 Act VI.