Betting Odds for No. 10 Oregon Ducks vs. No. 19 Colorado Buffaloes

The Ducks and Buffs are both off to 3-0 starts in 2023.

The No. 10 Oregon Ducks (3-0) are turning the page from their 55-10 win over the Hawaii Rainbow Warriors in week 3 as they prepare to face the No. 19 Colorado Buffaloes at home in week 4 to open Pac-12 conference play.

Bo Nix was in his usual form against the Rainbow Warriors, completing 21 of 27 passes for 247 yards and three touchdowns, while Oregon's run game bounced back after a hot-and-cold day against Texas Tech. Noah Whittington led the charge out of the backfield, logging 80 of the Ducks' 210 total rushing yards.

The Ducks had a dominant day on defense as well, limiting Hawaii to just 201 yards of offense and 14.3% conversion rate (2/14) on third down. Senior cornerback Khyree Jackson snagged his second interception in as many games and the defense recorded two sacks. 

Meanwhile, Colorado outlasted Colorado State in week 3 and came away with a 43-35 win at home in Boulder. 

Heading into this week's game, Oregon is the heavy betting favorite by almost three touchdowns, according to Sports Illustrated SportsBook. 

SI SportsBook Odds

Spread: Oregon -21.5 (-105) | Colorado +21.5 (-120)

Point total: 70.5 | Over (-111) | Under (-111)

Money Line: Oregon (-1613) | Colorado (+700)

Oregon vs. Colorado is scheduled to kick off at 12:30 pm PT in Eugene at Autzen Stadium. The game will be broadcast on ABC. 

The Ducks won the last time these two teams played in 2022 by a score of 49-10 on the road at Folsom Field in Boulder.

READ MORE: Oregon cracks top 10 in latest AP poll following blowout win over Hawaii

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