Colorado vs. Nebraska game picks, best bets: Week 2 college football predictions against the spread

What to expect as Deion Sanders puts his new-look Colorado team on the field against rival Nebraska as the Week 2 college football schedule kicks off

Year 1 at Colorado under Deion Sanders wasn't supposed to start like this, as all the experts and oddsmakers forecasted Prime's new-look roster wouldn't be able to compete. Then they went into natty runner-up TCU and pulled off the upset as three-touchdown underdogs. Now for Act 2, the Buffs return home to face Nebraska.

Shedeur Sanders had the best day for a Colorado quarterback ever, while two-way player Travis Hunter logged over 100 snaps, went over 100 yards receiving, and grabbed an interception. Freshman back Dylan Edwards was unstoppable, scoring four total touchdowns, including the game-winner on a fourth down pass.

Matt Rhule is still looking for his first win at the helm of the Cornhuskers program after the team lost yet another close game, this time at Minnesota, which mounted a late 10-0 scoring run that left Nebraska at 0-1 looking ahead to the Colorado game.

Here's what you need to know as Colorado and Nebraska face off to open the Week 2 college football schedule from a betting perspective.

Colorado vs. Nebraska game odds

Courtesy of SI Sportsbook

Line: Colorado -2.5 Track it live
Total: 59.5 points
Moneyline: CU -150 | NU +120
FPI pick: NU 58.7% | CU 41.3%

Related: Colorado vs. Nebraska picks, predictions, Week 2 college football odds, lines

Best bet

Colorado -2.5. Nebraska has a shot to win the game if it can maintain possession by running the ball more consistently. But if the Buffaloes will have the decided edge if they get on the board quickly and force the Huskers out of their comfort zone to throw the ball more. Watching Colorado defend against the run in the TCU game, and the perimeter speed it has to work with, that looks like a task it can live up to.

Spread consensus pick: 89 percent of bettors are siding with Colorado -3.5, up from 83 percent at the open

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Colorado vs. Nebraska schedule

When: Sat., Sept. 9
Time: 11 a.m. CT, 10 a.m. MT
TV: Fox network
Stream: fuboTV (Try for free)

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