Clemson vs. Louisville predictions, schedule, game time, TV channel, streaming

How to watch Clemson vs. Louisville on the Week 11 college football schedule with updated predictions and TV/streaming info

James Parks | Nov 12, 2022

Clemson vs. Louisville predictions, schedule, game time, TV channel, streaming /

Clemson vs. Louisville predictions, schedule, game time, TV channel, streaming

Clemson Tigers running back Will Shipley celebrates a touchdown during a college football game in the ACC. — Week 11 college football schedule: Clemson vs. Louisville / USA Today Images

How to watch

When: Sat., Nov. 12

Time: 3:30 p.m. Eastern

TV: ESPN network

Stream: fuboTV (Start your free trial)

Odds, point spread, betting lines

Game lines courtesy of SI Sportsbook and may change after publication

Point spread: Clemson comes into the game as 7 point favorites to defeat Louisville, according to the lines at SI Sportsbook.

Over/under: 52 points

Moneyline: Clemson -300, Louisville +200

FPI prediction: Clemson has the 76.2 percent chance to win the game outright, compared to Louisville (23.8%), according to the Football Power Index computers which simulate teams' seasons 20,000 times and predict winners using previous scores and schedules.

College Football HQ prediction: Our projections indicate that Clemson will defeat Louisville, 29-20, and cover the spread. Clemson -7

What you need to know

Louisville: The Cardinals have won their last four straight games and five of the last six and are 5 points away from being a one-loss football team. Malik Cunningham is one of the nation's premier dual threat quarterbacks, running for 11 touchdowns and passing for 8. Louisville, which is second in the ACC with 201 rushing yards per game. has played this series close recently, losing four times to the Tigers by a touchdown or less.

Clemson: Those all-important improvements on offense went up in smoke at Notre Dame last week with Will Shipley largely contained in the backfield and DJ Uiagalalei unable to generate a deep threat against the Irish, and now Clemson's shot at the College Football Playoff is in peril. It was No. 4 going into last week, and despite falling to 10th in the CFP rankings, is still the favorite to win the ACC title with one loss.

How to watch and stream college football this season

fuboTV provides full, total coverage of the top college football games on the 2022 schedule from the major TV networks as well as the SEC Network, Big Ten Network, ACC Network, Pac-12 Network, and others.

> Click here to start your free college football fuboTV trial

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Published Nov 12, 2022

JAMES PARKS

James Parks is the founder and publisher of College Football HQ. He previously covered football for 247Sports and CBS Interactive. College Football HQ joined the Sports Illustrated Fannation Network in 2022.